Protein: TMED9
Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25)

Gene: TMED9
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q9BVK6

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

888981

TMEDA
Transmembrane emp24 domain-containing protein 10

7

17

Small-scale

0.956

High

1146621

TMED2
Transmembrane emp24 domain-containing protein 2

4

18

Small-scale

0.887

High

1415433

TMED5
Transmembrane emp24 domain-containing protein 5

2

19

High-throughput

0.776

High

1415434

TMED7
Transmembrane emp24 domain-containing protein 7

2

19

Small-scale

0.776

High

1105869

TMED1
Transmembrane emp24 domain-containing protein 1

1

17

High-throughput

0.691

High

1281268

TMED4
Transmembrane emp24 domain-containing protein 4

1

18

High-throughput

0.691

High

1415435

TMED3
Transmembrane emp24 domain-containing protein 3

1

19

High-throughput

0.691

High

1415417

CHST8
Carbohydrate sulfotransferase 8

4

4

High-throughput

0.691

High

1350052

SPP2B
Signal peptide peptidase-like 2B

2

5

High-throughput

0.628

High

1415437

LIPG
Endothelial lipase

2

3

High-throughput

0.628

High

1415411

TMED9
Transmembrane emp24 domain-containing protein 9

1

17

Small-scale

0.618

High

1136346

EMC2
ER membrane protein complex subunit 2

2

3

High-throughput

0.611

High

1326895

EMC5
ER membrane protein complex subunit 5

2

2

High-throughput

0.611

High

1330379

EMC1
ER membrane protein complex subunit 1

2

3

High-throughput

0.611

High

225455

ITM2A
Integral membrane protein 2A

2

2

High-throughput

0.606

High

1394443

SC22A
Vesicle-trafficking protein SEC22a

2

5

High-throughput

0.606

High

773622

COPB2
Coatomer subunit beta'

2

11

Small-scale

0.601

High

546995

FGF3
Fibroblast growth factor 3

2

5

High-throughput

0.574

High

607643

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

3

Small-scale

0.573

High

396853

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

213696

AQP9
Aquaporin-9

2

1

High-throughput

0.553

High

130226

PGRC1
Membrane-associated progesterone receptor component 1

1

4

High-throughput

0.536

High

184222

RER1
Protein RER1

1

4

High-throughput

0.536

High

290264

TM1L1
TOM1-like protein 1

1

2

High-throughput

0.536

High

570967

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.536

High

699063

CALX
Calnexin

1

7

High-throughput

0.536

High

813202

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.536

High

1063586

GOGA2
Golgin subfamily A member 2

1

5

High-throughput

0.536

High

1132324

GOGB1
Golgin subfamily B member 1

1

2

High-throughput

0.536

High

1294495

VRK2
Serine/threonine-protein kinase VRK2

1

2

High-throughput

0.536

High

1352360

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.536

High

1382179

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

1386349

FAF2
FAS-associated factor 2

1

2

High-throughput

0.536

High

1394789

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.536

High

1415420

GORS2
Golgi reassembly-stacking protein 2

1

16

High-throughput

0.536

High

1415421

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

6

High-throughput

0.536

High

1415422

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

3

High-throughput

0.536

High

1415426

VAPA
Vesicle-associated membrane protein-associated protein A

1

7

High-throughput

0.536

High

1415429

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

251474

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

0

High-throughput

0.518

High

1351029

DDX54
ATP-dependent RNA helicase DDX54

1

0

High-throughput

0.518

High

505196

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.513

High

1333698

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

1415416

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1415428

PRAF1
Prenylated Rab acceptor protein 1

1

0

High-throughput

0.513

High

955541

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.501

High

724172

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.489

High

1142167

P2RY6
P2Y purinoceptor 6

1

6

High-throughput

0.489

High

1310370

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1361356

BRI3B
BRI3-binding protein

1

1

High-throughput

0.489

High

178382

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

218714

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

401415

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

535480

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

537824

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

567476

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.479

High

774591

BASI
Basigin

1

3

High-throughput

0.479

High

951395

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

1249179

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1334541

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1386562

OPTN
Optineurin

1

1

High-throughput

0.479

High

1393654

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1135080

CUL7
Cullin-7

1

0

High-throughput

0.458

High

877554

LHX1
LIM/homeobox protein Lhx1

1

3

High-throughput

0.457

High

916114

NKX25
Homeobox protein Nkx-2.5

1

3

High-throughput

0.457

High

1157056

NTRK3
NT-3 growth factor receptor

1

7

High-throughput

0.457

High

1415412

KLF16
Krueppel-like factor 16

1

4

High-throughput

0.457

High

1415431

LHX6
LIM/homeobox protein Lhx6

1

3

High-throughput

0.457

High

873303

COPD
Coatomer subunit delta

1

4

Small-scale

0.445

High

921767

COPB
Coatomer subunit beta

1

3

Small-scale

0.445

High

922014

COPA
Coatomer subunit alpha

1

11

Small-scale

0.445

High

1148932

SC23A
Protein transport protein Sec23A

1

17

Small-scale

0.445

High

1323760

S39AB
Zinc transporter ZIP11

1

4

High-throughput

0.445

High

1337935

ZNT7
Zinc transporter 7

1

10

High-throughput

0.445

High

1346774

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

10

High-throughput

0.445

High

1415415

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

5

High-throughput

0.445

High

1415432

S35A3
UDP-N-acetylglucosamine transporter

1

2

High-throughput

0.445

High

1415438

COPG1
Coatomer subunit gamma-1

1

5

Small-scale

0.445

High

1415414

YTHD1
YTH domain-containing family protein 1

1

2

High-throughput

0.439

High

164431

NRP1
Neuropilin-1

1

1

High-throughput

0.437

High

315965

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

373037

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

404384

GCR
Glucocorticoid receptor

1

11

High-throughput

0.437

High

541666

FGFR1
Fibroblast growth factor receptor 1

1

2

Small-scale

0.437

High

543281

UBL4A
Ubiquitin-like protein 4A

1

6

High-throughput

0.437

High

589582

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

696394

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769063

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

879426

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

914336

EFNA4
Ephrin-A4

1

1

High-throughput

0.437

High

944731

KLF3
Krueppel-like factor 3

1

5

High-throughput

0.437

High

947272

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

6

High-throughput

0.437

High

965207

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1005049

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1024810

VIGLN
Vigilin

1

1

High-throughput

0.437

High

1031525

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1117304

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

2

High-throughput

0.437

High

1125210

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.437

High

1126166

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1140784

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

1179134

TECT1
Tectonic-1

1

5

High-throughput

0.437

High

1229662

VIR
Protein virilizer homolog

1

3

High-throughput

0.437

High

1238805

TECT3
Tectonic-3

1

5

High-throughput

0.437

High

1255350

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1294251

GOLI
E3 ubiquitin-protein ligase RNF130

1

5

High-throughput

0.437

High

1348474

LNX1
E3 ubiquitin-protein ligase LNX

1

3

Small-scale

0.437

High

1367171

ESR2
Estrogen receptor beta

1

11

High-throughput

0.437

High

1397391

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

1415419

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1415423

T106B
Transmembrane protein 106B

1

4

High-throughput

0.437

High

1415427

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

1415430

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.437

High

964059

COPZ1
Coatomer subunit zeta-1

1

2

Small-scale

0.408

High

1149021

SC23B
Protein transport protein Sec23B

1

17

Small-scale

0.408

High

97259

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

256135

S19A2
Thiamine transporter 1

1

3

High-throughput

0.407

High

351250

MOT3
Monocarboxylate transporter 3

1

1

High-throughput

0.407

High

530316

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.407

High

722602

CTR1
High affinity cationic amino acid transporter 1

1

11

High-throughput

0.407

High

870303

S6A12
Sodium- and chloride-dependent betaine transporter

1

3

High-throughput

0.407

High

870411

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

3

High-throughput

0.407

High

1034056

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.407

High

1103359

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.407

High

1236301

MFSD5
Molybdate-anion transporter

1

5

High-throughput

0.407

High

1242213

NPAL3
NIPA-like protein 3

1

4

High-throughput

0.407

High

1242916

S39A4
Zinc transporter ZIP4

1

4

High-throughput

0.407

High

1313823

S15A3
Solute carrier family 15 member 3

1

2

High-throughput

0.407

High

1392005

PLPR2
Phospholipid phosphatase-related protein type 2

2

0

High-throughput

0.316

High

1415418

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

1415424

FBX28
F-box only protein 28

2

0

High-throughput

0.313

High

605153

KCRS
Creatine kinase S-type, mitochondrial

1

0

High-throughput

0.282

High

1332589

THAP8
THAP domain-containing protein 8

1

0

High-throughput

0.282

High

1415436

MTF2
Metal-response element-binding transcription factor 2

1

0

High-throughput

0.282

High

1349320

TBC15
TBC1 domain family member 15

1

0

High-throughput

0.279

Low

1394773

HIC2
Hypermethylated in cancer 2 protein

1

0

High-throughput

0.279

Low

1407157

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.279

Low

1415413

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

1415425

T161A
Transmembrane protein 161A

1

0

High-throughput

0.279

Low

820739

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.249

Low

1107162

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1122548

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.249

Low

1239659

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

Small-scale

0.249

Low

787507

GNL1
Guanine nucleotide-binding protein-like 1

1

0

High-throughput

0.232

Low

841242

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025