HitPredict

Interactor 1: COR1A (P31146)
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)
Gene: CORO1A

Interactor 2: CORO6 (Q6QEF8)
Coronin-6 (Coronin-like protein E) (Clipin-E)
Gene: CORO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 33961781, 26186194
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF1899~WD40, DUF1899~WD40_4, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0007015 - actin filament organization GO:0016477 - cell migration GO:0051015 - actin filament binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 472
+	Mm
		292620 COR1A_MOUSE (1-461): 9.77e-128: 379: 94.58		COR1B_MOUSE (1-470): 7.9e-116: 350: 68.05
+	Hs
		678302 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		COR1B_HUMAN (1-470): 2.03e-114: 347: 67.15
+	Hs
		1163301 CORO6_HUMAN (1-458): 1.61e-123: 369: 67.10		COR1B_HUMAN (1-470): 2.03e-114: 347: 67.15
+	Mm
		292586 COR1A_MOUSE (1-461): 9.77e-128: 379: 94.58		COR1A_MOUSE (1-463): 8.64e-110: 334: 67.46
+	Hs
		678297 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		COR2A_HUMAN (1-472): 8.75e-94: 295: 43.75
+	Sc
		987352 CORO_YEAST (1-439): 2.06e-103: 323: 38.73		CORO_YEAST (1-449): 1.48e-96: 306: 37.58
+	Hs
		678320 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		COR1C_HUMAN (2-209): 5.03e-19: 91.5: 13.06
+	Mm
		292621 COR1A_MOUSE (1-461): 9.77e-128: 379: 94.58		COR1C_MOUSE (2-209): 2.89e-19: 91.9: 13.06
+	Hs
		678289 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		POC1A_HUMAN (255-413): 4.63e-18: 88: 6.86
+	Hs
		678293 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		POC1B_HUMAN (255-413): 8.69e-18: 87.6: 7.91
+	Hs
		1163316 CORO6_HUMAN (1-458): 1.61e-123: 369: 67.10		COR1C_HUMAN (2-209): 5.03e-19: 91.5: 13.06
+	Hs
		1163297 CORO6_HUMAN (1-458): 1.61e-123: 369: 67.10		POC1A_HUMAN (255-413): 4.63e-18: 88: 6.86
+	Hs
		1309913 COR1B_HUMAN (1-458): 6.66e-116: 350: 63.90		COR1C_HUMAN (2-209): 5.03e-19: 91.5: 13.06
+	Hs
		903428 SNR40_HUMAN (2-158): 5.82e-29: 118: 16.15		WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55
+	Dm
		1358845 WDS_DROME (2-254): 7.37e-57: 193: 17.19		WDS_DROME (261-388): 1.53e-20: 94.6: 9.38
+	Hs
		1240442 POC1B_HUMAN (163-390): 6.16e-44: 162: 14.04		POC1A_HUMAN (255-413): 4.63e-18: 88: 6.86