HitPredict

Interactor 1: RAD16 (P31244)
DNA repair protein RAD16 (EC 3.6.4.-) (ATP-dependent helicase RAD16)
Gene: RAD16

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 790 Sc			1 134
+	Sc
		392337 RAD16_YEAST (1-790): 0: 641: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		470170 CHD8_HUMAN (75-788): 1.42e-171: 549: 22.16		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391915 CHD8_HUMAN (75-788): 1.42e-171: 549: 22.16		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sc
		687777 BTAF1_YEAST (126-789): 6.09e-141: 458: 22.22		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392077 BTAF1_YEAST (126-789): 6.09e-141: 458: 22.22		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392343 BTAF1_YEAST (126-789): 6.09e-141: 458: 22.22		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		391728 CHD9_HUMAN (85-788): 1.15e-155: 504: 21.17		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sp
		194283 FFT3_SCHPO (166-774): 3.49e-142: 443: 24.29		H2A1_SCHPO (10-133): 1.77e-51: 161: 56.80
+	Sp
		194284 FFT3_SCHPO (166-774): 3.49e-142: 443: 24.29		H2A2_SCHPO (10-131): 1.29e-51: 161: 58.54
+	Sc
		392076 FUN30_YEAST (177-776): 2.25e-137: 436: 22.82		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392339 FUN30_YEAST (177-776): 2.25e-137: 436: 22.82		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		391696 HLTF_HUMAN (99-787): 2.02e-147: 460: 24.73		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		1018640 CHD3_HUMAN (367-790): 4.85e-63: 232: 18.42		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		229433 SMCA5_HUMAN (487-788): 1.93e-58: 217: 20.79		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		229286 SMCA5_HUMAN (487-788): 1.93e-58: 217: 20.79		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391675 CHD3_HUMAN (367-790): 4.85e-63: 232: 18.42		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		229279 SMCA5_HUMAN (487-788): 1.93e-58: 217: 20.79		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		470059 SRCAP_HUMAN (620-763): 7.95e-17: 87.8: 35.42		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72