HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: EHMT1 (Q9H9B1)
Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D)
Gene: EHMT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 1298
+	Hs
		213385 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		EHMT1_HUMAN (12-1298): 0: 1058: 100.00
+	Mm
		590326 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		EHMT1_MOUSE (1-1298): 0: 1069: 88.39
+	Hs
		211969 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		EHMT1_HUMAN (12-1298): 0: 1058: 100.00
+	Hs
		679157 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		EHMT2_HUMAN (149-1291): 0: 686: 48.26
+	Hs
		213370 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		EHMT2_HUMAN (149-1291): 0: 686: 48.26
+	Hs
		211935 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		EHMT2_HUMAN (149-1291): 0: 686: 48.26
+	Hs
		203616 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		SUV91_HUMAN (949-1267): 1.53e-79: 270: 29.06
+	Hs
		958874 HXA4_HUMAN (30-286): 1.55e-35: 132: 23.90		ANKH1_HUMAN (762-1144): 4.59e-46: 184: 19.28
+	Hs
		446906 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		ANKH1_HUMAN (762-1144): 4.59e-46: 184: 19.28
+	Hs
		568030 HXB6_HUMAN (58-279): 7.84e-35: 128: 23.42		ANKH1_HUMAN (762-1144): 4.59e-46: 184: 19.28
+	Hs
		92414 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		E9PDP5_HUMAN (762-1144): 6.04e-46: 183: 19.28
+	Hs
		567802 HXB8_HUMAN (70-286): 2.34e-32: 122: 19.91		ANKH1_HUMAN (762-1144): 4.59e-46: 184: 19.28
+	Hs
		453058 HXB7_HUMAN (43-271): 4.77e-32: 120: 21.83		ANKH1_HUMAN (762-1144): 4.59e-46: 184: 19.28
+	Hs
		257599 HXA4_HUMAN (30-286): 1.55e-35: 132: 23.90		ANR17_HUMAN (798-1136): 1.82e-33: 143: 20.00
+	Hs
		257550 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		ANR17_HUMAN (798-1136): 1.82e-33: 143: 20.00
+	Hs
		257560 HXB6_HUMAN (58-279): 7.84e-35: 128: 23.42		ANR17_HUMAN (798-1136): 1.82e-33: 143: 20.00
+	Mm
		590489 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ANR17_MOUSE (798-1136): 2.25e-33: 143: 20.00
+	Hs
		166877 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		ANR28_HUMAN (846-1154): 3.62e-31: 135: 16.77
+	Hs
		257551 HXB7_HUMAN (43-271): 4.77e-32: 120: 21.83		ANR17_HUMAN (798-1136): 1.82e-33: 143: 20.00
+	Hs
		257562 HXA5_HUMAN (53-276): 6.78e-30: 116: 23.21		ANR17_HUMAN (798-1136): 1.82e-33: 143: 20.00