HitPredict

Interactor 1: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	26186194, 26496610, 28514442, 29162697, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 2346
+	Hs
		533842 KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Mm
		679428 KAP3_MOUSE (1-418): 3.5e-137: 400: 97.13		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Mm
		1194535 Q8K1M3_MOUSE (3-416): 4.69e-126: 371: 65.78		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Mm
		519440 KAP2_MOUSE (3-416): 5.39e-123: 364: 64.82		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Hs
		498293 KAP0_HUMAN (102-276): 8.25e-24: 103: 24.72		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		679385 KAP3_HUMAN (1-418): 3.91e-140: 408: 100.00		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Hs
		679387 KAP3_HUMAN (1-418): 3.91e-140: 408: 100.00		AKAP9_HUMAN (196-822): 2.21e-10: 68.9: 11.25
+	Hs
		533863 KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Hs
		533865 KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81		AKAP9_HUMAN (196-822): 2.21e-10: 68.9: 11.25
+	Hs
		498339 KAP0_HUMAN (102-276): 8.25e-24: 103: 24.72		CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73
+	Hs
		522594 KAP1_HUMAN (102-276): 7.34e-24: 104: 25.84		MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58
+	Hs
		528402 KAP1_HUMAN (102-276): 7.34e-24: 104: 25.84		MYH8_HUMAN (1820-2316): 2.84e-12: 75: 11.75