Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 40359616
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0005634 - nucleus
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 835
Sc

1 993
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 11Aug2025