HitPredict

Interactor 1: PDM2A (P31369)
POU domain protein 2, isoform A (Miti-mere) (Pdm-2) (Protein didymous) (dOct2) (dPOU-28)
Gene: pdm2

Interactor 2: HR78 (Q24142)
Nuclear hormone receptor HR78 (dHR78) (Nuclear receptor XR78E/F) (Nuclear receptor subfamily 2 group D member 1)
Gene: HR78

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	30995488
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 498 Dm			1 601
+	Dm
		1096320 PDM2B_DROME (50-482): 3.34e-117: 367: 100.00		HR78_DROME (1-601): 9.35e-147: 439: 100.00
+	Dm
		2210 A0A0B4JD55_DROME (169-456): 1.42e-45: 173: 24.43		HR78_DROME (1-601): 9.35e-147: 439: 100.00
+	Dm
		81148 B7YZU0_DROME (169-456): 8.99e-46: 173: 24.51		HR78_DROME (1-601): 9.35e-147: 439: 100.00
+	Dm
		1096263 Q9NHP8_DROME (149-448): 5.11e-47: 172: 16.41		HR78_DROME (1-601): 9.35e-147: 439: 100.00
+	Hs
		620133 PAX7_HUMAN (182-496): 2.97e-50: 180: 14.37		NR2C2_HUMAN (50-599): 6.54e-121: 372: 25.09
+	Hs
		525279 PAX7_HUMAN (182-496): 2.97e-50: 180: 14.37		NR2C1_HUMAN (9-596): 2.17e-117: 363: 26.02
+	Hs
		850855 PO5F1_HUMAN (212-496): 3.14e-56: 193: 37.11		NR0B1_HUMAN (397-595): 3.59e-64: 220: 23.98
+	Hs
		368919 PO2F1_HUMAN (141-495): 1.5e-50: 185: 38.44		ESR1_HUMAN (3-444): 1.74e-52: 191: 16.74
+	Mm
		590345 PO5F1_MOUSE (162-496): 2.67e-58: 198: 30.38		NR0B1_MOUSE (397-595): 2.22e-47: 174: 21.66
+	Hs
		368845 PO2F2_HUMAN (137-478): 4.43e-49: 177: 39.12		ESR1_HUMAN (3-444): 1.74e-52: 191: 16.74
+	Hs
		540778 PO2F1_HUMAN (141-495): 1.5e-50: 185: 38.44		RXRA_HUMAN (8-212): 4.4e-48: 176: 29.52
+	Hs
		447468 PO2F2_HUMAN (137-478): 4.43e-49: 177: 39.12		RXRA_HUMAN (8-212): 4.4e-48: 176: 29.52
+	Hs
		490085 PO2F1_HUMAN (141-495): 1.5e-50: 185: 38.44		COT1_HUMAN (19-181): 6.96e-45: 166: 37.81
+	Mm
		590278 PO5F1_MOUSE (162-496): 2.67e-58: 198: 30.38		ERR3_MOUSE (45-238): 2.28e-39: 152: 23.71
+	Hs
		447465 PO2F2_HUMAN (137-478): 4.43e-49: 177: 39.12		COT1_HUMAN (19-181): 6.96e-45: 166: 37.81
+	Dm
		558421 IPOU_DROME (148-464): 4.49e-50: 177: 28.75		7UP1_DROME (3-307): 7.5e-41: 157: 24.04
+	Dm
		558429 Q0IGS2_DROME (114-464): 2.59e-50: 177: 26.36		7UP1_DROME (3-307): 7.5e-41: 157: 24.04
+	Hs
		656396 PIT1_HUMAN (169-456): 5.04e-64: 211: 31.94		PPARG_HUMAN (43-142): 6.86e-23: 104: 48.00
+	Mm
		590354 PO5F1_MOUSE (162-496): 2.67e-58: 198: 30.38		ERR2_MOUSE (372-593): 2.88e-18: 89.5: 17.86
+	Mm
		139247 PO5F1_MOUSE (162-496): 2.67e-58: 198: 30.38		ERR1_MOUSE (384-593): 7.93e-18: 88: 20.76