Protein: STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (Transmembrane protein TMC)

Gene: STT3A
Organism: Homo sapiens
Interactions: 207
UniProt ID: P46977

Gene Ontology (top 5):
GO:0004579 - dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

417307

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

9

2

High-throughput

0.967

High

505142

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

2

1

Small-scale

0.789

High

813025

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

2

High-throughput

0.789

High

863451

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

2

High-throughput

0.691

High

863519

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.691

High

698470

CALX
Calnexin

3

2

High-throughput

0.657

High

863564

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.656

High

863552

UN93B
Protein unc-93 homolog B1

2

1

High-throughput

0.621

High

863449

TM258
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258

1

1

High-throughput

0.618

High

417999

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

2

High-throughput

0.611

High

863511

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

2

1

Small-scale

0.611

High

863501

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.586

High

241029

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

863551

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

5

High-throughput

0.575

High

540352

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.571

High

863466

CUL3
Cullin-3

2

0

High-throughput

0.559

High

863556

SG196
Protein O-mannose kinase

1

1

High-throughput

0.554

High

563394

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.552

High

130032

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.536

High

863438

PSN1
Presenilin-1

1

1

High-throughput

0.536

High

863468

MLEC
Malectin

1

1

High-throughput

0.536

High

863469

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.536

High

863506

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

863530

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

863547

DERL2
Derlin-2

1

1

High-throughput

0.536

High

217944

TGON2
Trans-Golgi network integral membrane protein 2

2

2

High-throughput

0.533

High

863563

FBX6
F-box only protein 6

2

1

High-throughput

0.533

High

863490

SARM1
NAD(+) hydrolase SARM1

1

1

High-throughput

0.528

High

863508

S15A3
Solute carrier family 15 member 3

2

2

High-throughput

0.521

High

863444

ACLY
ATP-citrate synthase

1

1

High-throughput

0.515

High

863445

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.515

High

863460

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

863513

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.513

High

863461

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

5

High-throughput

0.500

High

301366

WFS1
Wolframin

1

0

High-throughput

0.493

High

788865

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.493

High

623617

TFEB
Transcription factor EB

1

1

High-throughput

0.489

High

648334

USF1
Upstream stimulatory factor 1

1

1

High-throughput

0.489

High

726741

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.489

High

863459

TIE2
Angiopoietin-1 receptor

1

4

High-throughput

0.489

High

863473

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

863483

CEP78
Centrosomal protein of 78 kDa

1

1

High-throughput

0.489

High

863526

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.489

High

178211

NPC1
NPC intracellular cholesterol transporter 1

1

4

High-throughput

0.479

High

179839

BET1
BET1 homolog

1

1

High-throughput

0.479

High

291248

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

362953

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

466146

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

487070

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

534766

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

538545

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.479

High

580923

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

642708

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

711852

LTK
Leukocyte tyrosine kinase receptor

1

6

High-throughput

0.479

High

863439

EMD
Emerin

1

1

High-throughput

0.479

High

863440

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

863447

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

863448

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

863450

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

863456

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.479

High

863491

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

863492

SYNE3
Nesprin-3

1

1

High-throughput

0.479

High

863495

RHOU
Rho-related GTP-binding protein RhoU

1

18

High-throughput

0.479

High

863502

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

863512

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

863514

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

863520

RBCC1
RB1-inducible coiled-coil protein 1

1

1

High-throughput

0.479

High

863523

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

4

High-throughput

0.479

High

863524

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

863527

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

863531

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

863533

PLD4
5'-3' exonuclease PLD4

1

1

High-throughput

0.479

High

863536

RHOV
Rho-related GTP-binding protein RhoV

1

14

High-throughput

0.479

High

863539

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.479

High

863546

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

4

Small-scale

0.479

High

863572

DJB12
DnaJ homolog subfamily B member 12

1

5

High-throughput

0.479

High

863576

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

863579

SEC63
Translocation protein SEC63 homolog

1

5

High-throughput

0.479

High

680678

CATS
Cathepsin S

1

1

High-throughput

0.470

High

593734

PECA1
Platelet endothelial cell adhesion molecule

1

1

High-throughput

0.470

High

536716

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

766299

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

791169

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

799794

COIL
Coilin

1

0

High-throughput

0.458

High

863482

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

863497

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

863500

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.458

High

863507

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

863515

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

863542

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

863582

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

863475

NTRK3
NT-3 growth factor receptor

1

7

High-throughput

0.457

High

104117

F5H1C8
Solute carrier family 15 member 3

1

2

High-throughput

0.445

High

229220

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

1

High-throughput

0.445

High

863434

S6A12
Sodium- and chloride-dependent betaine transporter

1

1

High-throughput

0.445

High

863435

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

1

High-throughput

0.445

High

863463

NIPA4
Magnesium transporter NIPA4

1

2

High-throughput

0.445

High

863471

MFS10
Major facilitator superfamily domain-containing protein 10

1

4

High-throughput

0.445

High

863479

S35G1
Solute carrier family 35 member G1

1

3

High-throughput

0.445

High

863484

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

863487

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

863488

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

863517

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.445

High

863522

S35F5
Solute carrier family 35 member F5

1

2

High-throughput

0.445

High

126499

RHOD
Rho-related GTP-binding protein RhoD

1

18

High-throughput

0.437

High

293354

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

411551

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

413387

P53
Cellular tumor antigen p53

1

1

High-throughput

0.437

High

582555

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.437

High

588152

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

650083

FGFR3
Fibroblast growth factor receptor 3

1

5

High-throughput

0.437

High

694874

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

715476

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.437

High

767647

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

863437

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.437

High

863441

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.437

High

863443

RND2
Rho-related GTP-binding protein RhoN

1

18

High-throughput

0.437

High

863452

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

863454

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.437

High

863455

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.437

High

863457

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

863462

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.437

High

863465

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

863467

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

1

High-throughput

0.437

High

863470

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

863474

RHOH
Rho-related GTP-binding protein RhoH

1

14

High-throughput

0.437

High

863486

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

863494

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

863496

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

863498

VTCN1
V-set domain-containing T-cell activation inhibitor 1

1

1

Small-scale

0.437

High

863503

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.437

High

863510

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

863525

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

863528

FBX32
F-box only protein 32

1

1

High-throughput

0.437

High

863532

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.437

High

863534

FAF2
FAS-associated factor 2

1

1

High-throughput

0.437

High

863544

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.437

High

863545

RHBT2
Rho-related BTB domain-containing protein 2

1

13

High-throughput

0.437

High

863554

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.437

High

863555

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

863558

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.437

High

863560

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.437

High

863561

ANLN
Anillin

1

1

High-throughput

0.437

High

863565

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

863575

PD1L1
Programmed cell death 1 ligand 1

1

2

Small-scale

0.437

High

863578

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

863581

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.437

High

256003

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

863570

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

863573

S39A1
Zinc transporter ZIP1

1

0

High-throughput

0.426

High

529308

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

863476

S15A2
Solute carrier family 15 member 2

1

2

High-throughput

0.407

High

863485

S35F1
Solute carrier family 35 member F1

1

4

High-throughput

0.407

High

863489

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.407

High

863505

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

863580

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

4

High-throughput

0.407

High

210176

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

0

High-throughput

0.306

High

863442

CAV2
Caveolin-2

2

0

High-throughput

0.298

High

286173

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.282

High

181615

CETN3
Centrin-3

1

0

High-throughput

0.279

Low

625244

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.279

Low

863518

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

863559

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.279

Low

863568

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.279

Low

863541

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

863566

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

0

Small-scale

0.251

Low

128847

MEN1
Menin

1

0

High-throughput

0.249

Low

279303

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

349865

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.249

Low

415420

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.249

Low

567295

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.249

Low

830313

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

863436

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

863446

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

High-throughput

0.249

Low

863453

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

863472

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

863477

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

863478

DUS7
Dual specificity protein phosphatase 7

1

0

High-throughput

0.249

Low

863499

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

863504

SL9A9
Sodium/hydrogen exchanger 9

1

0

Small-scale

0.249

Low

863509

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

863521

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

863529

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

863535

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

863537

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

863538

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

863540

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

Small-scale

0.249

Low

863543

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.249

Low

863548

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.249

Low

863549

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

863550

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

863553

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.249

Low

863557

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

863567

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

863569

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.249

Low

863571

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

863574

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

863577

DYH2
Dynein axonemal heavy chain 2

1

0

High-throughput

0.249

Low

863583

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

863516

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.238

Low

863562

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.238

Low

143411

E2F3
Transcription factor E2F3

1

0

Small-scale

0.232

Low

863458

TAGL
Transgelin

1

0

High-throughput

0.232

Low

863464

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

863480

CTL4
Choline transporter-like protein 4

1

0

High-throughput

0.232

Low

863481

KLH22
Kelch-like protein 22

1

0

High-throughput

0.232

Low

863493

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025