HitPredict

Interactor 1: TPS2 (P31688)
Trehalose-phosphatase (EC 3.1.3.12) (Trehalose synthase complex catalytic subunit TPS2) (Trehalose-6-phosphate phosphatase) (TPP)
Gene: TPS2

Interactor 2: TPS1 (Q00764)
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit (EC 2.4.1.15) (General glucose sensor subunit 1) (Glycogen metabolism control protein GLC6) (Trehalose synthase complex catalytic subunit TPS1) (Trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase)
Gene: TPS1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 9194697, 11805826, 16554755, 16429126, 20489023, 37968396, 9837904
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, molecular sieving, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Glyco_transf_20~Glyco_transf_20
Common GO terms GO:0003825 - alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
GO:0004805 - trehalose-phosphatase activity
GO:0005829 - cytosol
GO:0005946 - alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
GO:0005992 - trehalose biosynthetic process
and 2 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 896
Sc

1 495
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024