Protein: PSA2
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)

Gene: PSA2, PSMA2
Organism: Homo sapiens
Interactions: 191
UniProt ID: P25787

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0000932 - P-body
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637316

PSA1
Proteasome subunit alpha type-1

14

18

Small-scale

0.984

High

637626

PSA4
Proteasome subunit alpha type-4

12

20

Small-scale

0.984

High

637663

PSA6
Proteasome subunit alpha type-6

10

19

Small-scale

0.977

High

156224

PSA7
Proteasome subunit alpha type-7

7

18

Small-scale

0.974

High

637625

PSA3
Proteasome subunit alpha type-3

8

20

Small-scale

0.973

High

637732

PSB7
Proteasome subunit beta type-7

8

20

Small-scale

0.972

High

637649

PSB2
Proteasome subunit beta type-2

8

20

Small-scale

0.972

High

637632

PSB4
Proteasome subunit beta type-4

8

19

Small-scale

0.970

High

637634

PSB5
Proteasome subunit beta type-5

8

19

Small-scale

0.966

High

637630

PSB9
Proteasome subunit beta type-9

7

19

Small-scale

0.963

High

594448

PSB1
Proteasome subunit beta type-1

6

20

Small-scale

0.955

High

637648

PSB3
Proteasome subunit beta type-3

6

19

Small-scale

0.955

High

637631

PSA5
Proteasome subunit alpha type-5

5

20

Small-scale

0.934

High

637633

PSB6
Proteasome subunit beta type-6

5

20

Small-scale

0.934

High

637640

PSB10
Proteasome subunit beta type-10

5

20

Small-scale

0.918

High

637629

PSB8
Proteasome subunit beta type-8

5

19

Small-scale

0.916

High

637667

PRS4
26S proteasome regulatory subunit 4

5

20

Small-scale

0.915

High

637668

PRS8
26S proteasome regulatory subunit 8

4

20

Small-scale

0.902

High

121684

PSD11
26S proteasome non-ATPase regulatory subunit 11

4

20

Small-scale

0.895

High

637669

PRS10
26S proteasome regulatory subunit 10B

4

20

Small-scale

0.895

High

637676

PSME1
Proteasome activator complex subunit 1

4

18

Small-scale

0.895

High

572857

PRS6A
26S proteasome regulatory subunit 6A

3

20

Small-scale

0.861

High

637689

PSME4
Proteasome activator complex subunit 4

3

8

Small-scale

0.861

High

637728

PSMG2
Proteasome assembly chaperone 2

3

8

Small-scale

0.861

High

637753

PSME2
Proteasome activator complex subunit 2

3

18

Small-scale

0.861

High

637624

PSA2
Proteasome subunit alpha type-2

3

19

Small-scale

0.853

High

637639

PRS7
26S proteasome regulatory subunit 7

3

20

Small-scale

0.847

High

637642

PRS6B
26S proteasome regulatory subunit 6B

3

20

Small-scale

0.847

High

637759

POMP
Proteasome maturation protein

3

7

Small-scale

0.847

High

130747

PSDE
26S proteasome non-ATPase regulatory subunit 14

6

20

Small-scale

0.721

High

637763

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

5

17

Small-scale

0.712

High

637658

PSMD4
26S proteasome non-ATPase regulatory subunit 4

5

12

Small-scale

0.709

High

314731

PSMG1
Proteasome assembly chaperone 1

4

5

Small-scale

0.694

High

637666

PSME3
Proteasome activator complex subunit 3

1

18

High-throughput

0.691

High

637719

PSMA8
Proteasome subunit alpha-type 8

1

19

High-throughput

0.691

High

637761

FBX7
F-box only protein 7

3

5

Small-scale

0.680

High

121936

PSD12
26S proteasome non-ATPase regulatory subunit 12

3

20

Small-scale

0.667

High

198544

PSMD3
26S proteasome non-ATPase regulatory subunit 3

3

9

Small-scale

0.667

High

637723

PSMF1
Proteasome inhibitor PI31 subunit

3

6

Small-scale

0.667

High

637734

PSMD1
26S proteasome non-ATPase regulatory subunit 1

3

20

Small-scale

0.667

High

637690

PSMD6
26S proteasome non-ATPase regulatory subunit 6

3

20

Small-scale

0.662

High

637679

PSMD2
26S proteasome non-ATPase regulatory subunit 2

3

20

Small-scale

0.656

High

637680

CUL1
Cullin-1

3

8

Small-scale

0.656

High

637739

PSMG3
Proteasome assembly chaperone 3

4

5

Small-scale

0.642

High

637655

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

3

9

Small-scale

0.640

High

637675

UBE3A
Ubiquitin-protein ligase E3A

3

18

Small-scale

0.640

High

637659

TERA
Transitional endoplasmic reticulum ATPase

1

9

Small-scale

0.618

High

345965

MYC
Myc proto-oncogene protein

2

5

High-throughput

0.611

High

637651

PSMD7
26S proteasome non-ATPase regulatory subunit 7

2

20

Small-scale

0.611

High

637671

SKP1
S-phase kinase-associated protein 1

2

10

Small-scale

0.611

High

637699

AKIR2
Akirin-2

2

8

Small-scale

0.611

High

637758

PSD13
26S proteasome non-ATPase regulatory subunit 13

2

10

Small-scale

0.611

High

637749

UBQL2
Ubiquilin-2

2

20

Small-scale

0.595

High

637657

RD23B
UV excision repair protein RAD23 homolog B

2

20

Small-scale

0.584

High

637694

ADRM1
Proteasomal ubiquitin receptor ADRM1

2

9

Small-scale

0.584

High

637701

DDI2
Protein DDI1 homolog 2

2

20

Small-scale

0.584

High

637703

ECM29
Proteasome adapter and scaffold protein ECM29

2

11

Small-scale

0.584

High

637727

FBXW7
F-box/WD repeat-containing protein 7

2

5

Small-scale

0.584

High

92602

E9PMD8
Proteasome 26S subunit, ATPase 3

1

20

High-throughput

0.575

High

108925

H0YKT8
Proteasome subunit beta

1

19

High-throughput

0.575

High

637700

PSMG4
Proteasome assembly chaperone 4

2

4

High-throughput

0.574

High

637662

SEM1
26S proteasome complex subunit SEM1

2

3

Small-scale

0.571

High

496337

TAU
Microtubule-associated protein tau

2

6

High-throughput

0.552

High

336367

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

362832

FINC
Fibronectin

1

5

High-throughput

0.536

High

506288

MBL2
Mannose-binding protein C

1

2

High-throughput

0.536

High

508828

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

528580

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.536

High

637650

PSN1
Presenilin-1

1

4

High-throughput

0.536

High

637652

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.536

High

637660

PCBP3
Poly(rC)-binding protein 3

1

2

High-throughput

0.536

High

637691

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

11

High-throughput

0.536

High

637706

RBP10
Ran-binding protein 10

1

3

High-throughput

0.536

High

637709

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

5

High-throughput

0.536

High

637713

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

19

High-throughput

0.536

High

637737

SLX1
Structure-specific endonuclease subunit SLX1

1

5

High-throughput

0.536

High

637745

AKIR1
Akirin-1

1

8

High-throughput

0.536

High

637752

AMFR
E3 ubiquitin-protein ligase AMFR

1

12

High-throughput

0.536

High

607588

NDKB
Nucleoside diphosphate kinase B

1

2

High-throughput

0.515

High

171476

UBD
Ubiquitin D

1

20

Small-scale

0.501

High

637627

IKBA
NF-kappa-B inhibitor alpha

1

6

Small-scale

0.501

High

637674

CCNA1
Cyclin-A1

1

2

Small-scale

0.501

High

316794

KLF8
Krueppel-like factor 8

1

17

High-throughput

0.500

High

637682

KLF5
Krueppel-like factor 5

1

17

High-throughput

0.500

High

637740

KLF16
Krueppel-like factor 16

1

17

High-throughput

0.500

High

637750

KLF15
Krueppel-like factor 15

1

17

High-throughput

0.500

High

245878

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.493

High

637716

CACL1
CDK2-associated and cullin domain-containing protein 1

1

9

High-throughput

0.489

High

637747

HOME3
Homer protein homolog 3

1

3

High-throughput

0.481

High

135370

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

6

High-throughput

0.479

High

160390

AURKA
Aurora kinase A

1

8

High-throughput

0.479

High

226565

PRKN
E3 ubiquitin-protein ligase parkin

1

20

Small-scale

0.479

High

243956

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

255517

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

275539

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

3

High-throughput

0.479

High

294389

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

302925

HEXI1
Protein HEXIM1

1

6

High-throughput

0.479

High

304786

MFN2
Mitofusin-2

1

4

High-throughput

0.479

High

324234

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.479

High

329374

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.479

High

397786

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.479

High

437910

HS90B
Heat shock protein HSP 90-beta

1

4

Small-scale

0.479

High

474930

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

Small-scale

0.479

High

475359

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.479

High

487144

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

488128

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

4

High-throughput

0.479

High

501706

BIP
Endoplasmic reticulum chaperone BiP

1

6

Small-scale

0.479

High

503467

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

551983

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

569212

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

570478

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

6

High-throughput

0.479

High

637628

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

637635

3MG
DNA-3-methyladenine glycosylase

1

1

High-throughput

0.479

High

637636

NOS2
Nitric oxide synthase, inducible

1

5

High-throughput

0.479

High

637637

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

637638

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

1

Small-scale

0.479

High

637641

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.479

High

637643

MAP1B
Microtubule-associated protein 1B

1

5

High-throughput

0.479

High

637644

YAP1
Transcriptional coactivator YAP1

1

8

High-throughput

0.479

High

637645

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

5

Small-scale

0.479

High

637646

TCPG
T-complex protein 1 subunit gamma

1

1

Small-scale

0.479

High

637653

PLK1
Serine/threonine-protein kinase PLK1

1

15

Small-scale

0.479

High

637654

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.479

High

637656

RD23A
UV excision repair protein RAD23 homolog A

1

20

Small-scale

0.479

High

637661

FBXW4
F-box/WD repeat-containing protein 4

1

6

Small-scale

0.479

High

637664

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.479

High

637665

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

637670

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

Small-scale

0.479

High

637672

EF1A1
Elongation factor 1-alpha 1

1

1

Small-scale

0.479

High

637673

RNF4
E3 ubiquitin-protein ligase RNF4

1

9

High-throughput

0.479

High

637677

DUS4
Dual specificity protein phosphatase 4

1

2

High-throughput

0.479

High

637678

PAK2
Serine/threonine-protein kinase PAK 2

1

6

High-throughput

0.479

High

637681

CUL4A
Cullin-4A

1

8

High-throughput

0.479

High

637684

TRI14
Tripartite motif-containing protein 14

1

8

High-throughput

0.479

High

637685

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

6

High-throughput

0.479

High

637686

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

5

Small-scale

0.479

High

637688

RBM39
RNA-binding protein 39

1

4

High-throughput

0.479

High

637692

UBE3C
Ubiquitin-protein ligase E3C

1

20

Small-scale

0.479

High

637693

NEDD8
NEDD8

1

14

Small-scale

0.479

High

637695

MK06
Mitogen-activated protein kinase 6

1

5

High-throughput

0.479

High

637696

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

637697

LARP7
La-related protein 7

1

6

High-throughput

0.479

High

637698

MIDN
Midnolin

1

5

High-throughput

0.479

High

637702

TET5C
Terminal nucleotidyltransferase 5C

1

2

High-throughput

0.479

High

637704

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

637705

DESI1
Desumoylating isopeptidase 1

1

6

Small-scale

0.479

High

637707

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

637708

SEML
Putative protein SEM1, isoform 2

1

3

High-throughput

0.479

High

637710

MOB3C
MOB kinase activator 3C

1

6

High-throughput

0.479

High

637711

MEPCE
7SK snRNA methylphosphate capping enzyme

1

4

High-throughput

0.479

High

637712

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

637714

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

Small-scale

0.479

High

637715

GOLI
E3 ubiquitin-protein ligase RNF130

1

18

High-throughput

0.479

High

637718

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

637720

RBCC1
RB1-inducible coiled-coil protein 1

1

3

High-throughput

0.479

High

637722

ASB11
Ankyrin repeat and SOCS box protein 11

1

2

High-throughput

0.479

High

637724

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

17

High-throughput

0.479

High

637725

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

637726

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

Small-scale

0.479

High

637729

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

637730

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

5

Small-scale

0.479

High

637735

TCPH
T-complex protein 1 subunit eta

1

1

Small-scale

0.479

High

637736

ANM1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.479

High

637738

PAAF1
Proteasomal ATPase-associated factor 1

1

7

Small-scale

0.479

High

637741

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

10

Small-scale

0.479

High

637742

ATG5
Autophagy protein 5

1

3

High-throughput

0.479

High

637743

TXNIP
Thioredoxin-interacting protein

1

3

Small-scale

0.479

High

637744

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

637748

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

637751

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.479

High

637755

FZR1
Fizzy-related protein homolog

1

11

High-throughput

0.479

High

637756

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.479

High

637757

UBQL1
Ubiquilin-1

1

20

High-throughput

0.479

High

637760

NINL
Ninein-like protein

1

3

High-throughput

0.479

High

637762

TRAF6
TNF receptor-associated factor 6

1

7

High-throughput

0.479

High

637731

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

637733

CDC5L
Cell division cycle 5-like protein

1

0

Small-scale

0.458

High

637746

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

637754

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

686

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

20

High-throughput

0.445

High

401443

JUN
Transcription factor Jun

1

7

High-throughput

0.445

High

625745

CXCR2
C-X-C chemokine receptor type 2

1

1

Small-scale

0.445

High

239498

EIF1B
Eukaryotic translation initiation factor 1b

1

3

High-throughput

0.437

High

384292

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

637687

GRM2
Metabotropic glutamate receptor 2

1

6

High-throughput

0.437

High

637721

DDI1
Protein DDI1 homolog 1

1

20

High-throughput

0.437

High

637764

INSI2
Insulin-induced gene 2 protein

1

3

Small-scale

0.437

High

637683

DAG1
Dystroglycan 1

1

0

Small-scale

0.426

High

637647

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

637717

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.407

High


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Last updated: 15 Jul 2024