HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 1363
+	Hs
		729333 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		VGFR3_HUMAN (1-1363): 0: 982: 100.00
+	Hs
		729374 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		VGFR3_HUMAN (1-1363): 0: 982: 100.00
+	Hs
		243261 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		RET_HUMAN (801-1176): 1.25e-74: 273: 40.63
+	Hs
		738254 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98
+	Hs
		452492 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		PGFRB_HUMAN (19-555): 1.14e-123: 413: 22.80
+	Hs
		507875 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Hs
		243293 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79
+	Hs
		243277 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Hs
		609471 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53
+	Hs
		434302 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		RET_HUMAN (801-1176): 1.25e-74: 273: 40.63
+	Hs
		608081 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79
+	Hs
		508145 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Hs
		507864 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Mm
		1142038 DNJA3_MOUSE (2-387): 1.71e-113: 341: 25.31		MUSK_MOUSE (2-142): 4.36e-11: 69.7: 13.48
+	Hs
		169212 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25
+	Hs
		608166 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79