HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0007283 - spermatogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Hs			1 890
+	Hs
		435551 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		411313 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		243262 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		243254 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		243261 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Hs
		441552 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		507875 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		435729 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		411469 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		674347 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56
+	Hs
		243277 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		243305 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56
+	Mm
		1142038 DNJA3_MOUSE (2-387): 1.71e-113: 341: 25.31		MUSK_MOUSE (42-268): 1.58e-26: 118: 16.67
+	Hs
		508145 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		507864 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		609471 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR3_HUMAN (7-315): 1.59e-17: 89.8: 14.60
+	Hs
		636250 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56
+	Hs
		411515 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		434302 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Hs
		169212 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		MUSK_HUMAN (42-257): 7.52e-27: 119: 16.59