HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Hs			1 1374
+	Hs
		507875 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		681463 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54
+	Dm
		448256 Q9VFV9_DROME (1-397): 1.49e-137: 400: 58.77		INSR_DROME (24-883): 2.43e-128: 441: 17.09
+	Hs
		411615 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		243277 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		243425 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54
+	Hs
		243255 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		609471 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		508145 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		412302 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		411313 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		INSR_HUMAN (111-395): 4.12e-41: 167: 36.27
+	Hs
		435551 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		384352 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		243254 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		INSR_HUMAN (111-395): 4.12e-41: 167: 36.27
+	Hs
		243262 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		243251 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		243669 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		ALK_HUMAN (109-386): 2.69e-32: 139: 32.99
+	Hs
		411469 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		INSR_HUMAN (111-395): 4.12e-41: 167: 36.27
+	Hs
		435729 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		385330 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77