HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	12757707, 32814053
Identification Methods	in-gel kinase assay, protein kinase assay, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	phosphorylation reaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 815
+	Hs
		568597 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Mm
		578258 KS6A3_MOUSE (81-455): 9.03e-94: 301: 24.81		ATX1_MOUSE (1-815): 0: 1271: 86.89