Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17535800 |
| Identification Methods | enzymatic study, in-gel kinase assay, protein kinase assay |
| Interaction Type | direct interaction, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, PH~SH3_9 |
| Common GO terms | GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0030027 - lamellipodium GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0043066 - negative regulation of apoptotic process and 1 others more... |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
