HitPredict

Interactor 1: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Interactor 2: I13R1 (P78552)
Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1)
Gene: IL13RA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	12207328
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004896 - cytokine receptor activity GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0019221 - cytokine-mediated signaling pathway GO:0019955 - cytokine binding and 1 others more... GO:0043235 - receptor complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 427
+	Hs
		682253 IL2RG_HUMAN (1-369): 6.04e-109: 325: 100.00		IL2RG_HUMAN (105-427): 2.75e-45: 162: 19.39
+	Hs
		540448 IL2RG_HUMAN (1-369): 6.04e-109: 325: 100.00		IL2RB_HUMAN (131-399): 7.71e-17: 84.6: 14.34
+	Hs
		622725 IL2RG_HUMAN (1-369): 6.04e-109: 325: 100.00		IL4RA_HUMAN (130-423): 1.3e-16: 84.3: 15.36
+	Hs
		616945 IL2RG_HUMAN (1-369): 6.04e-109: 325: 100.00		PTPRD_HUMAN (4-405): 1.13e-15: 81.5: 8.27
+	Hs
		665605 EPHB2_HUMAN (24-348): 4.44e-49: 179: 12.39		EPHA7_HUMAN (10-420): 9.69e-52: 188: 10.91
+	Hs
		964638 IL5RA_HUMAN (14-295): 5.9e-46: 164: 18.87		IL5RA_HUMAN (34-427): 8.6e-57: 194: 21.85
+	Hs
		265771 EPHA7_HUMAN (34-348): 3.58e-45: 168: 10.98		CRLF1_HUMAN (18-342): 7.66e-55: 189: 19.17
+	Hs
		560467 PRLR_HUMAN (51-294): 8.34e-46: 167: 16.28		PRLR_HUMAN (124-398): 1.09e-51: 185: 19.38
+	Hs
		665399 EPHA3_HUMAN (7-348): 6.47e-43: 161: 10.30		EPHA7_HUMAN (10-420): 9.69e-52: 188: 10.91
+	Hs
		665477 EPHA8_HUMAN (44-345): 1.64e-41: 157: 8.72		EPHA7_HUMAN (10-420): 9.69e-52: 188: 10.91
+	Hs
		500940 GHR_HUMAN (48-294): 1.74e-45: 166: 14.96		GHR_HUMAN (108-382): 9.29e-47: 172: 17.11
+	Hs
		1056195 I13R2_HUMAN (10-274): 3.74e-47: 166: 22.14		SDK2_HUMAN (7-377): 9.6e-19: 91.1: 8.97
+	Hs
		622738 I13R2_HUMAN (10-274): 3.74e-47: 166: 22.14		IL4RA_HUMAN (130-423): 1.3e-16: 84.3: 15.36
+	Hs
		489962 I13R2_HUMAN (10-274): 3.74e-47: 166: 22.14		PTPRF_HUMAN (10-262): 2.85e-14: 77.3: 11.32
+	Hs
		1031984 I13R2_HUMAN (10-274): 3.74e-47: 166: 22.14		PTPRS_HUMAN (4-407): 2.93e-13: 74.2: 8.74
+	Hs
		701712 IL5RA_HUMAN (14-295): 5.9e-46: 164: 18.87		IL3RB_HUMAN (128-393): 7.31e-14: 75.8: 13.50
+	Hs
		616944 EPHA8_HUMAN (44-345): 1.64e-41: 157: 8.72		PTPRD_HUMAN (4-405): 1.13e-15: 81.5: 8.27
+	Hs
		548791 CSF2R_HUMAN (48-336): 1.46e-44: 159: 16.12		IL3RB_HUMAN (128-393): 7.31e-14: 75.8: 13.50
+	Hs
		265768 CRLF1_HUMAN (51-254): 2.59e-44: 159: 18.43		PTPRS_HUMAN (4-407): 2.93e-13: 74.2: 8.74