HitPredict

Interactor 1: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.573

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 236
+	Hs
		171310 EPHB6_HUMAN (42-348): 3.92e-44: 164: 12.50		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		665584 EPHB2_HUMAN (24-348): 4.44e-49: 179: 12.39		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980379 EPHA7_HUMAN (34-348): 3.58e-45: 168: 10.98		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		872428 EPHA5_HUMAN (43-348): 8.3e-45: 166: 12.87		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980374 I13R2_HUMAN (10-274): 3.74e-47: 166: 22.14		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		964702 IL5RA_HUMAN (14-295): 5.9e-46: 164: 18.87		TEN3_HUMAN (148-233): 1.23e-12: 68.9: 19.30
+	Hs
		132250 PTPRF_HUMAN (22-271): 2.77e-15: 79.4: 9.58		DLL1_HUMAN (43-236): 1.42e-21: 94.7: 25.56
+	Hs
		132258 PTPRS_HUMAN (20-241): 1.94e-14: 77.1: 11.79		DLL1_HUMAN (43-236): 1.42e-21: 94.7: 25.56