HitPredict

Interactor 1: HNRH1 (P31943)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: HNRNPH1

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28977470, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 342
+	Hs
		1031444 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		878718 HNRH2_HUMAN (1-449): 9.37e-73: 237: 96.21		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		878702 HNRH2_HUMAN (1-449): 9.37e-73: 237: 96.21		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903196 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		516438 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		682755 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		878631 HNRH2_HUMAN (1-449): 9.37e-73: 237: 96.21		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		855191 HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		682660 HNRH3_HUMAN (10-86): 1.84e-10: 64.1: 32.47		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		582462 NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		855163 HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		582421 NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903236 SART3_HUMAN (2-217): 8.31e-16: 82.1: 23.89		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		855007 HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		582176 NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		197022 SART3_HUMAN (2-217): 8.31e-16: 82.1: 23.89		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40