HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37039823
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 963
+	Hs
		646740 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP11_HUMAN (6-937): 0: 717: 44.60
+	Hs
		777027 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		683179 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		910137 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP21_HUMAN (651-928): 3.71e-63: 226: 25.00
+	Hs
		777029 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		927636 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP21_HUMAN (651-928): 3.71e-63: 226: 25.00
+	Mm
		910281 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		UBP8_MOUSE (727-932): 8.66e-58: 218: 34.45
+	Hs
		646698 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		647384 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP22_HUMAN (764-928): 2.7e-60: 216: 28.33
+	Hs
		777025 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		683552 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP32_HUMAN (850-954): 1.99e-21: 103: 28.30
+	Hs
		909722 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		683479 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		909724 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		683481 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		927203 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		927206 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		647032 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		647034 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		904758 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45