HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: GAPD1 (Q14C86)
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6)
Gene: GAPVD1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	33961781, 35271311, 15324660, 24255178, 17353931, 28514442
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1478
+	Hs
		909576 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GAPD1_HUMAN (1-1478): 0: 2079: 100.00
+	Hs
		683194 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		IQGA1_HUMAN (6-515): 6.57e-125: 429: 15.09
+	Hs
		909664 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DAB2P_HUMAN (62-602): 5.14e-111: 382: 16.72
+	Hs
		683429 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DAB2P_HUMAN (62-602): 5.14e-111: 382: 16.72
+	Hs
		910133 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NGAP_HUMAN (69-628): 8.13e-78: 283: 14.24
+	Hs
		683798 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		NGAP_HUMAN (69-628): 8.13e-78: 283: 14.24
+	Hs
		909931 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SYGP1_HUMAN (72-507): 6.42e-73: 270: 15.00
+	Mm
		99940 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		683638 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SYGP1_HUMAN (72-507): 6.42e-73: 270: 15.00
+	Mm
		99950 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		909774 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RASL3_HUMAN (94-635): 9.53e-71: 260: 16.72
+	Hs
		683797 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RABX5_HUMAN (1221-1477): 1.03e-67: 239: 20.83
+	Hs
		108670 G9K388_HUMAN (5-238): 2.44e-159: 448: 66.95		RIN3_HUMAN (1208-1475): 5.18e-48: 189: 17.69
+	Hs
		598455 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NF1_HUMAN (144-468): 2.57e-58: 225: 18.26
+	Hs
		598433 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		NF1_HUMAN (144-468): 2.57e-58: 225: 18.26
+	Mm
		910233 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		NF1_MOUSE (144-468): 2.05e-57: 222: 17.98
+	Mm
		926782 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		NF1_MOUSE (144-468): 2.05e-57: 222: 17.98
+	Hs
		909924 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANR27_HUMAN (1214-1472): 7.13e-56: 214: 20.15
+	Hs
		683558 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RIN3_HUMAN (1208-1475): 5.18e-48: 189: 17.69
+	Mm
		910298 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		VP9D1_MOUSE (1221-1475): 5.12e-44: 173: 15.94