HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	24366813, 33961781, 36931259, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 622
+	Hs
		909922 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FRMD6_HUMAN (1-622): 1.67e-171: 503: 100.00
+	Hs
		909498 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		683305 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		683735 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L5_HUMAN (5-598): 2.32e-127: 393: 14.73
+	Hs
		663970 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		663962 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		910025 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		683710 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		910185 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		683836 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		505612 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		204644 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		204620 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		683499 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FRMD5_HUMAN (1-528): 6e-107: 335: 19.04
+	Hs
		640229 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		640216 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Mm
		910287 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		FRM4A_MOUSE (12-334): 6.2e-85: 288: 19.64
+	Mm
		910323 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		909595 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Hs
		683372 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75