HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: AGAP1 (Q9UPQ3)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)
Gene: AGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 857
+	Hs
		910161 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		AGAP1_HUMAN (1-857): 0: 850: 100.00
+	Hs
		927661 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		AGAP1_HUMAN (1-857): 0: 850: 100.00
+	Hs
		909925 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		AGAP3_HUMAN (4-827): 0: 768: 72.46
+	Hs
		683633 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		AGAP3_HUMAN (4-827): 0: 768: 72.46
+	Hs
		91531 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E7EUN2_HUMAN (26-857): 0: 722: 86.54
+	Hs
		683656 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		AGAP2_HUMAN (52-827): 0: 597: 52.94
+	Hs
		909582 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ACAP2_HUMAN (308-854): 7.28e-132: 414: 16.55
+	Hs
		910023 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		Q9H4D1_HUMAN (376-855): 5.28e-87: 295: 16.17
+	Hs
		683708 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		Q9H4D1_HUMAN (376-855): 5.28e-87: 295: 16.17
+	Hs
		927522 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		Q9H4D1_HUMAN (376-855): 5.28e-87: 295: 16.17
+	Hs
		909866 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARAP2_HUMAN (556-846): 2.29e-75: 271: 27.70
+	Hs
		683584 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ARAP2_HUMAN (556-846): 2.29e-75: 271: 27.70
+	Hs
		927353 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ARAP2_HUMAN (556-846): 2.29e-75: 271: 27.70
+	Mm
		910271 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GIT1_MOUSE (616-848): 7.53e-73: 256: 31.58
+	Mm
		910346 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GIT2_MOUSE (616-823): 4.77e-73: 255: 33.78
+	Mm
		926813 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		GIT1_MOUSE (616-848): 7.53e-73: 256: 31.58
+	Hs
		883468 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RIPK4_HUMAN (566-798): 1.5e-13: 76.7: 13.81
+	Hs
		683234 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RIPK4_HUMAN (566-798): 1.5e-13: 76.7: 13.81
+	Hs
		683652 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		Q96T11_HUMAN (566-798): 4.32e-13: 75.2: 13.81
+	Hs
		883471 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RIPK4_HUMAN (566-798): 1.5e-13: 76.7: 13.81