HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DUF1115~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 683
+	Hs
		202405 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202407 LSM6_HUMAN (4-75): 2.84e-27: 95.6: 25.00		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202544 LSM7_HUMAN (3-76): 1.31e-24: 89.8: 31.71		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202415 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202404 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202370 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Hs
		202350 LSM8_HUMAN (8-75): 2.53e-19: 76: 23.61		PRPF3_HUMAN (1-683): 0: 947: 100.00
+	Sc
		770327 RUXG_YEAST (7-76): 5.33e-22: 82.3: 50.69		PRP3_YEAST (243-670): 6.14e-102: 321: 25.83
+	Sc
		873657 RUXF_YEAST (5-73): 2.81e-21: 80.6: 24.29		PRP3_YEAST (243-670): 6.14e-102: 321: 25.83
+	Sc
		865979 LSM7_YEAST (3-75): 1.4e-18: 74.8: 30.95		PRP3_YEAST (243-670): 6.14e-102: 321: 25.83
+	Sc
		884824 LSM3_YEAST (4-72): 4.33e-10: 52.6: 28.57		PRP3_YEAST (243-670): 6.14e-102: 321: 25.83