HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15778465
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0019901 - protein kinase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 244
+	Hs
		893865 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		892304 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		901116 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RND3_HUMAN (1-244): 1.15e-81: 246: 100.00
+	Hs
		925173 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		892309 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		564469 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02
+	Hs
		436240 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48
+	Hs
		904423 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Mm
		935511 1433F_MOUSE (2-242): 1.72e-96: 284: 64.20		RHOC_MOUSE (22-213): 2.02e-92: 271: 49.48
+	Hs
		564472 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02
+	Hs
		646769 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Hs
		683240 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RND3_HUMAN (1-244): 1.15e-81: 246: 100.00
+	Hs
		893862 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		893927 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		904428 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		683235 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		545303 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89
+	Hs
		900349 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Hs
		892302 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75