Protein: PLEC
Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6)

Gene: PLEC
Organism: Mus musculus
Interactions: 45
UniProt ID: Q9QXS1

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0002102 - podosome
GO:0002162 - dystroglycan binding
GO:0002522 - leukocyte migration involved in immune response
GO:0003334 - keratinocyte development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993452

ACTH
Actin, gamma-enteric smooth muscle

1

20

Small-scale

0.647

High

1455879

PLEC
Plectin

1

17

High-throughput

0.618

High

1247226

NEB2
Neurabin-2

2

18

High-throughput

0.584

High

97989

RYR2
Ryanodine receptor 2

1

9

High-throughput

0.575

High

98081

DESP
Desmoplakin

1

17

High-throughput

0.575

High

547402

DMD
Dystrophin

1

19

High-throughput

0.575

High

591185

MET
Hepatocyte growth factor receptor

1

10

High-throughput

0.575

High

1317868

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.553

High

771729

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

6

High-throughput

0.536

High

1225141

CRK
Adapter molecule crk

1

14

High-throughput

0.536

High

1424027

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.536

High

236641

ITB3
Integrin beta-3

1

13

High-throughput

0.501

High

478561

ITB1
Integrin beta-1

1

14

High-throughput

0.501

High

509310

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

7

High-throughput

0.501

High

313365

COR1A
Coronin-1A

1

13

High-throughput

0.479

High

556542

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

1

High-throughput

0.479

High

723771

DESM
Desmin

1

20

Small-scale

0.479

High

947786

NPHP4
Nephrocystin-4

1

5

High-throughput

0.479

High

990062

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1180427

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

1

6

Small-scale

0.479

High

1189218

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

1233079

TEDC2
Tubulin epsilon and delta complex protein 2

1

3

High-throughput

0.479

High

1282701

FACD2
Fanconi anemia group D2 protein homolog

1

6

High-throughput

0.479

High

1297069

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

5

High-throughput

0.479

High

1297934

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.479

High

1362785

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

1408706

FOXP3
Forkhead box protein P3

1

2

High-throughput

0.479

High

1455880

NPHP1
Nephrocystin-1

1

1

High-throughput

0.479

High

1297437

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

549422

ITB2
Integrin beta-2

1

13

High-throughput

0.457

High

59520

A2AKD7
Alpha-1-syntrophin

1

11

High-throughput

0.445

High

905994

CAV3
Caveolin-3

1

9

High-throughput

0.445

High

1209204

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

Small-scale

0.445

High

1455838

SRCN1
SRC kinase signaling inhibitor 1

1

6

High-throughput

0.445

High

59660

A2AM57
Inversin

1

14

High-throughput

0.437

High

97664

E9PV60
WD repeat and FYVE domain containing 4

1

13

High-throughput

0.437

High

399181

CFAD
Complement factor D

1

8

High-throughput

0.437

High

789784

THB
Thyroid hormone receptor beta

1

11

High-throughput

0.437

High

1253546

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.437

High

1296416

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

11

High-throughput

0.437

High

1298366

MT21E
Protein-lysine methyltransferase METTL21E

1

5

High-throughput

0.437

High

1423668

RN138
E3 ubiquitin-protein ligase RNF138

1

8

Small-scale

0.437

High

1424218

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

Small-scale

0.437

High

1231081

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025