HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22706160
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 963
+	Hs
		683310 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		UBP4_HUMAN (1-963): 0: 908: 100.00
+	Hs
		646740 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		UBP11_HUMAN (6-937): 0: 717: 44.60
+	Hs
		683881 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		777027 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		910137 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		UBP21_HUMAN (651-928): 3.71e-63: 226: 25.00
+	Mm
		910281 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		UBP8_MOUSE (727-932): 8.66e-58: 218: 34.45
+	Hs
		777029 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		927636 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		UBP21_HUMAN (651-928): 3.71e-63: 226: 25.00
+	Hs
		646698 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		647384 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		UBP22_HUMAN (764-928): 2.7e-60: 216: 28.33
+	Hs
		683179 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06
+	Hs
		684150 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		684153 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		909722 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		909724 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		927203 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		927206 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		647032 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45
+	Hs
		647034 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22
+	Hs
		683479 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45