Protein: PTPRE
Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48)

Gene: PTPRE
Organism: Homo sapiens
Interactions: 58
UniProt ID: P23469

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

614649

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

7

17

High-throughput

0.958

High

658960

GRB2
Growth factor receptor-bound protein 2

5

20

Small-scale

0.925

High

658949

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

4

16

Small-scale

0.887

High

462987

YES
Tyrosine-protein kinase Yes

1

20

High-throughput

0.691

High

440372

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

658955

SHC1
SHC-transforming protein 1

1

17

Small-scale

0.618

High

658966

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.618

High

172481

XPO1
Exportin-1

2

14

High-throughput

0.611

High

658958

XPO2
Exportin-2

2

14

High-throughput

0.611

High

658975

SAAL1
Protein SAAL1

2

4

High-throughput

0.611

High

658979

XPO4
Exportin-4

2

7

High-throughput

0.611

High

362780

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.590

High

484057

PGFRB
Platelet-derived growth factor receptor beta

1

18

High-throughput

0.575

High

658964

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

2

Small-scale

0.561

High

658953

CALX
Calnexin

2

8

High-throughput

0.558

High

220863

XPOT
Exportin-T

1

13

High-throughput

0.536

High

658988

5MP1
eIF5-mimic protein 1

1

1

High-throughput

0.536

High

245870

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.513

High

129997

PGRC1
Membrane-associated progesterone receptor component 1

1

3

High-throughput

0.479

High

133947

IPO5
Importin-5

1

5

High-throughput

0.479

High

164528

TNPO2
Transportin-2

1

10

High-throughput

0.479

High

643412

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

658950

MK03
Mitogen-activated protein kinase 3

1

11

Small-scale

0.479

High

658951

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

1

High-throughput

0.479

High

658952

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

658954

MK01
Mitogen-activated protein kinase 1

1

11

Small-scale

0.479

High

658956

GDNF
Glial cell line-derived neurotrophic factor

1

1

High-throughput

0.479

High

658961

DLG1
Disks large homolog 1

1

6

High-throughput

0.479

High

658971

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.479

High

658972

TNPO1
Transportin-1

1

10

High-throughput

0.479

High

658973

TP4A1
Protein tyrosine phosphatase type IVA 1

1

3

High-throughput

0.479

High

658976

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.479

High

658978

IPO9
Importin-9

1

9

High-throughput

0.479

High

658980

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

High-throughput

0.479

High

658983

ABI2
Abl interactor 2

1

9

High-throughput

0.479

High

658985

COR1C
Coronin-1C

1

3

High-throughput

0.479

High

658986

BAIP2
BAR/IMD domain-containing adapter protein 2

1

2

High-throughput

0.479

High

658987

TNPO3
Transportin-3

1

15

High-throughput

0.479

High

532365

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

658957

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

658962

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.458

High

658968

ST134
Putative protein FAM10A4

1

1

High-throughput

0.445

High

658959

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

105355

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

334685

IPO7
Importin-7

1

11

High-throughput

0.437

High

571370

GLU2B
Glucosidase 2 subunit beta

1

3

High-throughput

0.437

High

658963

GANAB
Neutral alpha-glucosidase AB

1

4

High-throughput

0.437

High

658967

CERS3
Ceramide synthase 3

1

3

High-throughput

0.437

High

658970

WASF1
Actin-binding protein WASF1

1

3

High-throughput

0.437

High

658977

CERS2
Ceramide synthase 2

1

3

High-throughput

0.437

High

658982

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

1

High-throughput

0.437

High

658984

SE1L1
Protein sel-1 homolog 1

1

2

High-throughput

0.437

High

391725

STAT
Statherin

1

0

High-throughput

0.279

Low

658969

TMC1
Transmembrane channel-like protein 1

1

0

High-throughput

0.279

Low

658974

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

658981

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.279

Low

658965

YIF1B
Protein YIF1B

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025