HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: REEP3 (Q6NUK4)
Receptor expression-enhancing protein 3
Gene: REEP3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	36931259, 15778465
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 255
+	Hs
		909682 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		684326 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		927170 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		910029 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		909967 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		927531 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		927467 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		910038 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		REEP1_HUMAN (1-162): 1.58e-72: 222: 73.46
+	Hs
		647003 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		927540 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		REEP1_HUMAN (1-162): 1.58e-72: 222: 73.46
+	Hs
		683447 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		904717 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		647279 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		927402 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		REEP6_HUMAN (1-134): 2.18e-56: 181: 25.93
+	Hs
		683713 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	At
		788367 14331_ARATH (3-241): 4.5e-144: 405: 56.85		HA22K_ARATH (1-167): 1.06e-44: 150: 21.43
+	Hs
		683673 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		905052 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Zm
		42212 B6SRI4_MAIZE (1-247): 1.94e-144: 405: 57.83		A0A1D6NY22_MAIZE (13-61): 1.88e-17: 76.1: 30.61
+	Hs
		683272 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		REEP5_HUMAN (1-125): 8.94e-59: 186: 28.57