HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1076
+	Hs
		909758 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LUZP1_HUMAN (1-1076): 0: 616: 100.00
+	Hs
		684102 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MRCKA_HUMAN (1-362): 2.6e-17: 90.2: 17.96
+	Hs
		683875 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MYH11_HUMAN (259-776): 1.43e-16: 87.4: 10.15
+	Hs
		684096 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CCD18_HUMAN (34-415): 8e-15: 81.8: 18.69
+	Mm
		93548 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DESP_MOUSE (110-643): 8.06e-23: 108: 10.26
+	Mm
		926804 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH10_MOUSE (96-717): 2.5e-30: 132: 11.44
+	Mm
		926886 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MY18A_MOUSE (72-656): 5.5e-29: 128: 11.92
+	Hs
		684048 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PLEC_HUMAN (35-503): 1.33e-11: 71.4: 16.50
+	Hs
		725130 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH10_HUMAN (2-451): 8.79e-21: 101: 14.79
+	Hs
		684075 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Hs
		909658 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MRCKA_HUMAN (1-362): 2.6e-17: 90.2: 17.96
+	Hs
		728460 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH11_HUMAN (259-776): 1.43e-16: 87.4: 10.15
+	Hs
		551660 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DESP_HUMAN (110-643): 4.72e-23: 109: 9.89
+	Hs
		909653 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CCD18_HUMAN (34-415): 8e-15: 81.8: 18.69
+	Mm
		926855 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH9_MOUSE (234-788): 1.37e-17: 90.9: 9.48
+	Hs
		909625 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Hs
		724761 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Mm
		926835 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LIPA2_MOUSE (3-401): 3.13e-11: 69.9: 17.49
+	Hs
		522602 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH7_HUMAN (368-712): 2.03e-10: 67.4: 8.57
+	Mm
		926889 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		PLEC_MOUSE (3-390): 6.63e-09: 62.5: 19.86