HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 601
+	Hs
		909877 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK2_HUMAN (1-601): 0: 534: 100.00
+	Hs
		683964 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80
+	Hs
		625306 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		683974 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70
+	Hs
		684347 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYRK4_HUMAN (119-595): 5.24e-124: 377: 44.24
+	Hs
		414774 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13
+	Hs
		684022 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		684420 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYR1B_HUMAN (149-537): 1.88e-118: 366: 39.11
+	Hs
		909447 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80
+	Hs
		625334 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		909458 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70
+	Hs
		909547 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87
+	Hs
		910066 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK4_HUMAN (119-595): 5.24e-124: 377: 44.24
+	Hs
		909539 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Mm
		910255 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DYR1A_MOUSE (211-537): 3.58e-117: 367: 42.52
+	Hs
		910197 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1B_HUMAN (149-537): 1.88e-118: 366: 39.11
+	Hs
		926942 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70
+	Hs
		927021 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	At
		847169 14332_ARATH (3-248): 2.23e-144: 405: 58.47		AFC1_ARATH (176-537): 5.75e-111: 342: 31.97
+	Zm
		27099 B6SRI4_MAIZE (1-247): 1.94e-144: 405: 57.83		A0A1D6JDK3_MAIZE (161-535): 2.37e-55: 203: 33.63