HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36931259, 28514442
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 622
+	Hs
		909922 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FRMD6_HUMAN (1-622): 1.67e-171: 503: 100.00
+	Hs
		684003 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		684340 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		E41L5_HUMAN (5-598): 2.32e-127: 393: 14.73
+	Hs
		909498 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		663970 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		204621 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		910025 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		640217 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		910185 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		505612 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		204644 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		547003 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Hs
		640229 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		640086 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MOES_HUMAN (12-595): 1.26e-110: 345: 15.20
+	Hs
		204648 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		640230 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		684056 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Mm
		910287 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		FRM4A_MOUSE (12-334): 6.2e-85: 288: 19.64
+	Mm
		910323 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		909595 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75