HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: PKHF2 (Q9H8W4)
Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) (Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains) (EAPF) (PH and FYVE domain-containing protein 2) (Phafin-2) (Phafin2) (Zinc finger FYVE domain-containing protein 18)
Gene: PLEKHF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	16189514
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 249
+	Hs
		684147 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		FGD6_HUMAN (11-240): 1.14e-56: 196: 29.76
+	Hs
		909717 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FGD6_HUMAN (11-240): 1.14e-56: 196: 29.76
+	Hs
		909711 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FGD5_HUMAN (10-241): 5.66e-56: 194: 23.17
+	Hs
		927201 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		FGD6_HUMAN (11-240): 1.14e-56: 196: 29.76
+	Hs
		684355 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MTMR4_HUMAN (55-233): 6.29e-36: 136: 21.58
+	Hs
		909944 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RUFY1_HUMAN (3-220): 3.5e-40: 148: 21.08
+	Hs
		910087 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR4_HUMAN (55-233): 6.29e-36: 136: 21.58
+	Hs
		909535 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR3_HUMAN (51-217): 3.54e-32: 126: 22.60
+	Hs
		927439 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RUFY1_HUMAN (3-220): 3.5e-40: 148: 21.08
+	Hs
		927584 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMR4_HUMAN (55-233): 6.29e-36: 136: 21.58
+	Hs
		927016 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMR3_HUMAN (51-217): 3.54e-32: 126: 22.60
+	Hs
		647028 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		FGD6_HUMAN (11-240): 1.14e-56: 196: 29.76
+	Hs
		647024 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		FGD5_HUMAN (10-241): 5.66e-56: 194: 23.17
+	Hs
		683475 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		FGD6_HUMAN (11-240): 1.14e-56: 196: 29.76
+	Hs
		647212 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RUFY1_HUMAN (3-220): 3.5e-40: 148: 21.08
+	Hs
		159905 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		HGS_HUMAN (27-248): 1.55e-42: 155: 18.80
+	Hs
		647323 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		MTMR4_HUMAN (55-233): 6.29e-36: 136: 21.58
+	Hs
		683757 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		MTMR4_HUMAN (55-233): 6.29e-36: 136: 21.58
+	Hs
		683328 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		MTMR3_HUMAN (51-217): 3.54e-32: 126: 22.60
+	Hs
		904536 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		MTMR3_HUMAN (51-217): 3.54e-32: 126: 22.60