HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RASF1 (Q9NS23)
Ras association domain-containing protein 1
Gene: RASSF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20069457
Identification Methods	coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051726 - regulation of cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 344
+	Hs
		683910 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		RASF2_HUMAN (122-339): 1.48e-67: 217: 23.61
+	Hs
		397138 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KPCG_HUMAN (24-277): 2.91e-54: 190: 17.47
+	Hs
		841540 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RASF2_HUMAN (122-339): 1.48e-67: 217: 23.61
+	Hs
		841542 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RASF2_HUMAN (122-339): 1.48e-67: 217: 23.61
+	Hs
		397155 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KPCG_HUMAN (24-277): 2.91e-54: 190: 17.47
+	Hs
		646735 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RASF2_HUMAN (122-339): 1.48e-67: 217: 23.61
+	Hs
		566348 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Hs
		926956 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCZ_HUMAN (15-152): 6.03e-34: 133: 24.11
+	Hs
		683974 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KPCE_HUMAN (27-107): 4.59e-13: 72.2: 31.33
+	Hs
		909585 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KPCD1_HUMAN (50-183): 2.44e-19: 91: 19.40
+	Hs
		909458 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KPCE_HUMAN (27-107): 4.59e-13: 72.2: 31.33
+	Hs
		927495 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCD2_HUMAN (50-276): 1.17e-20: 95.3: 16.08
+	Hs
		927067 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCD1_HUMAN (50-183): 2.44e-19: 91: 19.40
+	Hs
		926942 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCE_HUMAN (27-107): 4.59e-13: 72.2: 31.33
+	Hs
		926957 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCD_HUMAN (23-114): 2.53e-12: 69.9: 21.74
+	Hs
		566293 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Hs
		646824 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCZ_HUMAN (15-152): 6.03e-34: 133: 24.11
+	Hs
		646908 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCD1_HUMAN (50-183): 2.44e-19: 91: 19.40
+	Hs
		646812 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCE_HUMAN (27-107): 4.59e-13: 72.2: 31.33
+	Hs
		646820 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCT_HUMAN (30-114): 9.76e-11: 64.9: 27.06