Protein: EDC3
Enhancer of mRNA-decapping protein 3

Gene: EDC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P39998

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031087 - deadenylation-independent decapping of nuclear-transcribed mRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

812040

DHH1
ATP-dependent RNA helicase DHH1

8

2

Small-scale

0.972

High

816646

EDC3
Enhancer of mRNA-decapping protein 3

7

2

Small-scale

0.953

High

816663

DCP2
m7GpppN-mRNA hydrolase

16

4

Small-scale

0.764

High

816675

DCP1
mRNA-decapping enzyme subunit 1

7

0

Small-scale

0.714

High

645431

XRN1
5'-3' exoribonuclease 1

4

1

Small-scale

0.692

High

796733

TTL
Probable tubulin--tyrosine ligase PBY1

4

0

Small-scale

0.666

High

503496

RS28B
Small ribosomal subunit protein eS28B

3

1

Small-scale

0.663

High

816659

LSM8
LSM2-LSM8 complex subunit LSM8

3

2

High-throughput

0.652

High

816676

RS28A
Small ribosomal subunit protein eS28A

2

1

Small-scale

0.643

High

721621

RENT1
ATP-dependent helicase NAM7

3

2

Small-scale

0.641

High

816656

SCD6
Protein SCD6

2

1

Small-scale

0.619

High

816652

SSB2
Ribosome-associated molecular chaperone SSB2

3

1

High-throughput

0.611

High

721966

XPO1
Exportin-1

2

2

High-throughput

0.606

High

709386

HRR25
Casein kinase I homolog HRR25

2

0

Small-scale

0.585

High

678683

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

2

1

Small-scale

0.584

High

809256

MET30
F-box protein MET30

2

0

High-throughput

0.565

High

526781

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

394593

EF1A
Elongation factor 1-alpha

2

0

Small-scale

0.547

High

806282

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.529

High

816650

LSM4
LSM complex subunit LSM4

1

0

High-throughput

0.518

High

816670

MYO5
Myosin-5

1

0

High-throughput

0.518

High

816658

LSM1
LSM1-LSM7 complex subunit LSM1

1

2

High-throughput

0.515

High

816665

LSM3
LSM complex subunit LSM3

1

1

High-throughput

0.515

High

795870

LSM2
LSM complex subunit LSM2

1

2

High-throughput

0.508

High

518032

SSBP1
Single-stranded nucleic acid-binding protein

1

2

Small-scale

0.501

High

602471

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

642394

MCK1
Protein kinase MCK1

1

2

High-throughput

0.501

High

816648

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.493

High

661167

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.486

High

757984

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.486

High

816660

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.486

High

816673

SRL2
Protein SRL2

1

0

High-throughput

0.486

High

441141

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

779239

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.479

High

816666

H3
Histone H3

1

1

High-throughput

0.479

High

801835

KSP1
Serine/threonine-protein kinase KSP1

1

0

Small-scale

0.460

High

427294

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

435120

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435987

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

438704

SC160
Protein SCP160

1

0

Small-scale

0.458

High

531754

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.458

High

579454

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

707189

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

797743

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

816653

TM108
Protein TMA108

1

0

High-throughput

0.458

High

816654

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

816661

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

816662

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

816668

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

Small-scale

0.458

High

816669

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

816671

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

816672

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

816674

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

524053

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

544992

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

816655

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.445

High

816664

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

810811

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

386721

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

453615

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

486467

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.426

High

510528

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

592277

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

752301

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

816657

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

808508

TEM1
Protein TEM1

2

0

High-throughput

0.307

High

807809

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.288

High

757939

SKT5
Chitin synthase regulator SKT5

1

0

High-throughput

0.265

Low

816647

FIR1
Factor interacting with REF2

1

0

High-throughput

0.265

Low

816649

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

816651

DSE1
Protein DSE1

1

0

High-throughput

0.265

Low

812326

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

816667

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025