HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: MTMR4 (Q9NYA4)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1195
+	Hs
		910087 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		927584 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		909535 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		927016 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		909534 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR2_HUMAN (7-630): 0: 716: 32.77
+	Mm
		926899 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MTMR1_MOUSE (14-630): 0: 727: 28.37
+	Hs
		309464 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Mm
		926821 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MTMR5_MOUSE (161-802): 7.58e-152: 501: 22.07
+	Hs
		927581 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMRA_HUMAN (6-625): 2.53e-157: 490: 19.89
+	Hs
		684310 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		910000 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		309444 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Hs
		927499 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		684147 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		909717 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		927201 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		647028 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		909944 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		927439 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		647212 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00