HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28514442, 35271311, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 505
+	Hs
		437930 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		111934 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		K9JA46_HUMAN (1-504): 0: 655: 62.96
+	Hs
		431574 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90A_HUMAN (1-504): 0: 655: 62.96
+	At
		878278 HSOP2_ARATH (3-543): 4.73e-97: 307: 41.86		HS902_ARATH (1-504): 0: 631: 49.74
+	Dm
		365481 Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42		HSP83_DROME (1-504): 0: 669: 57.69
+	Hs
		538123 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		438464 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		432195 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		438533 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		174561 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		432268 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		174556 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		684788 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87
+	Hs
		538353 SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Sc
		366262 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSP82_YEAST (1-504): 0: 585: 45.53
+	Sc
		543696 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSC82_YEAST (1-504): 0: 582: 44.66
+	Hs
		174598 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Sc
		365721 STI1_YEAST (2-182): 1.26e-14: 78.8: 21.51		HSP82_YEAST (1-504): 0: 585: 45.53
+	Sc
		543117 STI1_YEAST (2-182): 1.26e-14: 78.8: 21.51		HSC82_YEAST (1-504): 0: 582: 44.66
+	Hs
		1162526 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		Q6PK50_HUMAN (1-301): 1.17e-138: 405: 80.26