HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: DMAP1 (Q9NPF5)
DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1)
Gene: DMAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.644

The method score is based on:

Property Details
Experiments 10888872, 33961781
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1616
Hs

1 467
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025