Protein: ATG12
Ubiquitin-like protein ATG12 (Autophagy-related protein 12)

Gene: ATG12
Organism: Saccharomyces cerevisiae S288C
Interactions: 153
UniProt ID: P38316

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0000422 - autophagy of mitochondrion
GO:0005829 - cytosol
GO:0006501 - C-terminal protein lipidation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748407

ATG5
Autophagy protein 5

13

3

Small-scale

0.985

High

748343

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

7

3

Small-scale

0.750

High

748384

ATG16
Autophagy protein 16

7

0

Small-scale

0.717

High

748356

ATG3
Autophagy-related protein 3

5

4

Small-scale

0.711

High

748396

ATG10
Ubiquitin-like-conjugating enzyme ATG10

4

0

Small-scale

0.656

High

748392

ATG17
Autophagy-related protein 17

3

0

Small-scale

0.651

High

748408

ATG31
Autophagy-related protein 31

3

0

Small-scale

0.603

High

715887

ATG19
Autophagy-related protein 19

2

1

Small-scale

0.595

High

745974

ATG8
Autophagy-related protein 8

2

3

Small-scale

0.595

High

748335

ATG12
Ubiquitin-like protein ATG12

1

0

Small-scale

0.586

High

748412

ATG11
Autophagy-related protein 11

2

0

Small-scale

0.585

High

372820

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

1

High-throughput

0.536

High

387990

ADT1
ADP,ATP carrier protein 1

1

2

High-throughput

0.536

High

578529

SEC18
Vesicular-fusion protein SEC18

1

1

High-throughput

0.536

High

596638

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

689334

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

690916

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

1

High-throughput

0.536

High

748365

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

748366

ARC1
tRNA-aminoacylation cofactor ARC1

1

1

High-throughput

0.536

High

748370

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

Small-scale

0.529

High

423457

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.513

High

434528

OAT
Ornithine aminotransferase

1

0

High-throughput

0.513

High

540082

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.513

High

748337

YHJ3
Uncharacterized protein YHR033W

1

0

High-throughput

0.513

High

748344

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.513

High

748349

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.513

High

748359

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

748363

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.513

High

748372

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.513

High

748409

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.513

High

748364

ATG18
Autophagy-related protein 18

1

1

Small-scale

0.501

High

748369

ATG1
Serine/threonine-protein kinase ATG1

1

1

Small-scale

0.501

High

342008

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.500

High

423839

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.500

High

424488

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.500

High

498506

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

581290

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.500

High

583216

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.500

High

575889

ADT3
ADP,ATP carrier protein 3

1

2

High-throughput

0.489

High

676008

XPO1
Exportin-1

1

1

High-throughput

0.489

High

703883

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.489

High

748339

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.489

High

748390

RPN7
26S proteasome regulatory subunit RPN7

1

1

High-throughput

0.489

High

748402

RPN5
26S proteasome regulatory subunit RPN5

1

1

High-throughput

0.489

High

342366

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.479

High

368006

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.479

High

378338

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.479

High

381454

GAL1
Galactokinase

1

0

High-throughput

0.479

High

604399

CLH
Clathrin heavy chain

1

0

High-throughput

0.479

High

636606

CDC48
Cell division control protein 48

1

0

High-throughput

0.479

High

748374

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.479

High

748397

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

748403

ATG34
Autophagy-related protein 34

1

1

Small-scale

0.479

High

747572

ATG14
Autophagy-related protein 14

1

0

Small-scale

0.458

High

748368

VPS4
Vacuolar protein sorting-associated protein 4

1

1

High-throughput

0.457

High

454303

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.457

High

454598

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.457

High

520823

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.457

High

554634

HSP26
Heat shock protein 26

1

1

High-throughput

0.457

High

556010

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.457

High

575949

ADT2
ADP,ATP carrier protein 2

1

2

High-throughput

0.457

High

748379

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

High-throughput

0.457

High

491054

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493822

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

409897

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.439

High

440125

AAP
Arginine attenuator peptide

1

0

High-throughput

0.438

High

471021

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.438

High

732087

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.438

High

747662

YBY7
UPF0303 protein YBR137W

1

0

High-throughput

0.438

High

748377

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.438

High

748399

FDH1
Formate dehydrogenase 1

1

0

High-throughput

0.438

High

511121

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

698204

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

2

High-throughput

0.417

High

478144

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

748350

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

748405

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

588988

TYR1
Prephenate dehydrogenase [NADP(+)]

2

0

High-throughput

0.316

High

593526

DBP3
ATP-dependent RNA helicase DBP3

2

0

High-throughput

0.295

High

748393

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.295

High

341794

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.279

Low

440881

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.279

Low

448497

PRTB
Cerevisin

1

0

High-throughput

0.279

Low

485714

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

562225

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.279

Low

697586

KA122
Importin beta-like protein KAP122

1

0

High-throughput

0.279

Low

703787

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.279

Low

748338

PPX1
Polyphosphatase

1

0

High-throughput

0.279

Low

748340

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.279

Low

748342

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.279

Low

748346

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.279

Low

748351

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.279

Low

748355

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.279

Low

748360

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

748375

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.279

Low

748406

RPN6
26S proteasome regulatory subunit RPN6

1

0

High-throughput

0.279

Low

748411

TCB1
Tricalbin-1

1

0

High-throughput

0.279

Low

748348

PRM9
Pheromone-regulated membrane protein 9

1

0

High-throughput

0.265

Low

360860

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low

370985

REP1
Partitioning protein REP1

1

0

High-throughput

0.261

Low

440023

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.261

Low

549669

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

558618

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.261

Low

619569

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.261

Low

699333

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

748352

IMB4
Importin subunit beta-4

1

0

High-throughput

0.261

Low

748357

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

748361

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

748376

ACT
Actin

1

0

High-throughput

0.261

Low

748410

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.261

Low

141783

YL269
Putative uncharacterized protein YLR269C

1

0

High-throughput

0.238

Low

396177

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.238

Low

500610

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.238

Low

536216

PMS1
DNA mismatch repair protein PMS1

1

0

High-throughput

0.238

Low

593139

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.238

Low

612522

MAK32
Protein MAK32

1

0

High-throughput

0.238

Low

659153

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.238

Low

688522

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.238

Low

696717

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.238

Low

697138

ANP1
Mannan polymerase II complex ANP1 subunit

1

0

High-throughput

0.238

Low

697618

DRI1
Putative RNA-binding protein involved in heterochromatin assembly

1

0

High-throughput

0.238

Low

701167

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.238

Low

713689

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.238

Low

734147

SRL3
Protein SRL3

1

0

High-throughput

0.238

Low

748208

YB47
Uncharacterized protein YBR197C

1

0

High-throughput

0.238

Low

748336

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.238

Low

748341

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.238

Low

748345

STN1
Protein STN1

1

0

High-throughput

0.238

Low

748347

MET30
F-box protein MET30

1

0

High-throughput

0.238

Low

748353

DDI1
DNA damage-inducible protein 1

1

0

High-throughput

0.238

Low

748354

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.238

Low

748358

FLX1
Mitochondrial FAD carrier protein FLX1

1

0

High-throughput

0.238

Low

748362

ZNF1
Respiratory transcription factor ZNF1

1

0

High-throughput

0.238

Low

748367

DS1P1
Dihydrosphingosine 1-phosphate phosphatase LCB3

1

0

High-throughput

0.238

Low

748371

FHN1
Non-classical export protein 2 homolog 1

1

0

High-throughput

0.238

Low

748373

TEX1
Protein TEX1

1

0

High-throughput

0.238

Low

748378

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

High-throughput

0.238

Low

748380

IRC15
Increased recombination centers protein 15

1

0

High-throughput

0.238

Low

748381

GIP3
GLC7-interacting protein 3

1

0

High-throughput

0.238

Low

748382

RMT2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.238

Low

748383

TMA23
Protein TMA23

1

0

High-throughput

0.238

Low

748385

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.238

Low

748386

LIC4
Protein ATC1/LIC4

1

0

High-throughput

0.238

Low

748387

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.238

Low

748388

CYK2
Cytokinesis protein 2

1

0

High-throughput

0.238

Low

748389

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

High-throughput

0.238

Low

748391

NEJ1
Non-homologous end-joining protein 1

1

0

High-throughput

0.238

Low

748394

SNA4
Protein SNA4

1

0

High-throughput

0.238

Low

748395

YD129
Uncharacterized protein YDL129W

1

0

High-throughput

0.238

Low

748398

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.238

Low

748400

YO392
Putative uncharacterized protein YOR392W

1

0

High-throughput

0.238

Low

748401

YP142
Putative uncharacterized protein YPL142C

1

0

High-throughput

0.238

Low

748404

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024