HitPredict

Interactor 1: OTX1 (P32242)
Homeobox protein OTX1 (Orthodenticle homolog 1)
Gene: OTX1

Interactor 2: KRA15 (Q9BYS1)
Keratin-associated protein 1-5 (High sulfur keratin-associated protein 1.5) (Keratin-associated protein 1.5)
Gene: KRTAP1-5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.613

Property	Details
Experiments	27107012, 32296183, unassigned1304
Identification Methods	two hybrid, barcode fusion genetics two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Hs			1 174
+	Hs
		686434 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA11_HUMAN (1-164): 1.78e-30: 110: 79.88
+	Hs
		686515 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR411_HUMAN (1-174): 7.6e-27: 102: 31.12
+	Hs
		686492 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA13_HUMAN (1-173): 1.02e-24: 95.6: 77.59
+	Hs
		686509 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR412_HUMAN (1-174): 2.08e-22: 90.6: 29.41
+	Hs
		686419 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR101_HUMAN (2-174): 1.67e-18: 82.1: 30.16
+	Hs
		686420 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR103_HUMAN (2-149): 3.08e-17: 77.5: 26.67
+	Hs
		686424 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR109_HUMAN (3-134): 1.07e-16: 77.1: 26.32
+	Hs
		686422 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR107_HUMAN (34-173): 1.11e-14: 72.5: 26.03
+	Hs
		686423 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR108_HUMAN (1-138): 3.2e-14: 70.1: 31.69
+	Hs
		686416 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR122_HUMAN (19-174): 5.75e-14: 67.1: 26.92
+	Hs
		686425 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR10B_HUMAN (10-139): 1.85e-12: 65.5: 29.23
+	Hs
		686418 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR124_HUMAN (22-113): 1.73e-13: 65.1: 29.35
+	Hs
		686511 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA98_HUMAN (74-174): 1.43e-12: 64: 29.70
+	Hs
		686513 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA93_HUMAN (3-124): 1.92e-11: 60.9: 26.23
+	Hs
		686514 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA92_HUMAN (74-174): 4.33e-11: 60.1: 27.72
+	Hs
		686421 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR105_HUMAN (51-171): 4.1e-10: 59: 24.83
+	Hs
		473266 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA23_HUMAN (19-110): 1.41e-10: 57.8: 32.98
+	Hs
		686512 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA94_HUMAN (74-174): 4.61e-10: 57.1: 27.72
+	Hs
		686417 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR123_HUMAN (15-106): 2.73e-09: 53.6: 35.48
+	Hs
		686415 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR121_HUMAN (15-106): 6.37e-09: 52.8: 34.41