HitPredict - High confidence protein-protein interactions

Interactor 1: OTX2 (P32243)
Homeobox protein OTX2 (Orthodenticle homolog 2)
Gene: OTX2

Interactor 2: OTX2 (P32243)
Homeobox protein OTX2 (Orthodenticle homolog 2)
Gene: OTX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus and 17 others more... GO:0006357 - regulation of transcription by RNA polymerase II GO:0007411 - axon guidance GO:0008190 - eukaryotic initiation factor 4E binding GO:0008589 - regulation of smoothened signaling pathway GO:0030426 - growth cone GO:0030900 - forebrain development GO:0030901 - midbrain development GO:0032991 - protein-containing complex GO:0040019 - positive regulation of embryonic development GO:0040036 - regulation of fibroblast growth factor receptor signaling pathway GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0065003 - protein-containing complex assembly GO:0071542 - dopaminergic neuron differentiation GO:0090009 - primitive streak formation GO:1990837 - sequence-specific double-stranded DNA binding GO:2000543 - positive regulation of gastrulation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	289
Hs

1	289

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Last updated: 15 Jul 2024