HitPredict

Interactor 1: IMB3 (P32337)
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)
Gene: PSE1

Interactor 2: NUP57 (P48837)
Nucleoporin NUP57 (Nuclear pore protein NUP57)
Gene: NUP57

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.685

Property	Details
Experiments	11387327, 10688190, 9864357, 22357553
Identification Methods	affinity chromatography technology, two hybrid, filter binding, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Sc			1 541
+	Sc
		687969 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU145_YEAST (4-393): 1.5e-42: 165: 21.52
+	Sc
		687954 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU159_YEAST (5-321): 5.81e-20: 96.3: 15.46
+	Sc
		767683 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP57_YEAST (1-541): 1.51e-93: 297: 100.00
+	Sc
		687986 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU100_YEAST (12-279): 1.74e-12: 72.4: 29.41
+	Sc
		687985 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NUP49_YEAST (45-298): 1.04e-09: 62.8: 23.11
+	Sc
		687987 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU116_YEAST (1-282): 6.89e-09: 60.8: 22.95
+	Ce
		136533 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		O01576_CAEEL (1-280): 3.23e-10: 65.1: 23.53
+	Ce
		1341732 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		Q9XWK3_CAEEL (1-212): 3e-10: 64.7: 24.54
+	Sc
		767656 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU159_YEAST (5-321): 5.81e-20: 96.3: 15.46
+	Sc
		767712 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU100_YEAST (12-279): 1.74e-12: 72.4: 29.41
+	Sc
		697934 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		SLA1_YEAST (3-292): 4.47e-12: 71.2: 16.43
+	Sc
		767710 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP49_YEAST (45-298): 1.04e-09: 62.8: 23.11
+	Sc
		767713 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU116_YEAST (1-282): 6.89e-09: 60.8: 22.95
+	Hs
		858024 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NUP98_HUMAN (68-329): 1.41e-14: 79.4: 16.10
+	Hs
		155553 TNPO2_HUMAN (214-1089): 4.77e-66: 242: 11.98		NUP98_HUMAN (68-329): 1.41e-14: 79.4: 16.10
+	Tt
		101907 G0SGZ5_CHATD (6-924): 2.31e-68: 250: 15.76		NU145_CHATD (33-307): 4.22e-12: 71.3: 23.83
+	Hs
		727300 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU214_HUMAN (17-255): 5.03e-10: 64.6: 22.76
+	Ce
		248166 O62332_CAEEL (246-1088): 2.4e-63: 234: 11.19		P91457_CAEEL (1-280): 1.39e-14: 78.9: 18.40
+	Hs
		834652 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46
+	Hs
		155550 TNPO2_HUMAN (214-1089): 4.77e-66: 242: 11.98		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46