Protein: CD14
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form]

Gene: CD14
Organism: Homo sapiens
Interactions: 55
UniProt ID: P08571

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0001819 - positive regulation of cytokine production
GO:0001847 - opsonin receptor activity
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0002752 - cell surface pattern recognition receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

237458

TLR2
Toll-like receptor 2

3

10

Small-scale

0.834

High

354808

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.656

High

441008

LBP
Lipopolysaccharide-binding protein

3

0

Small-scale

0.632

High

120124

TLR4
Toll-like receptor 4

1

10

Small-scale

0.618

High

179922

TLR3
Toll-like receptor 3

1

10

Small-scale

0.618

High

441035

TLR9
Toll-like receptor 9

1

10

Small-scale

0.618

High

441036

TLR8
Toll-like receptor 8

1

10

Small-scale

0.618

High

441038

TLR7
Toll-like receptor 7

1

10

Small-scale

0.618

High

441018

FSTL1
Follistatin-related protein 1

2

0

Small-scale

0.593

High

441045

IRAK3
Interleukin-1 receptor-associated kinase 3

1

0

High-throughput

0.589

High

364639

TRFL
Lactotransferrin

1

0

Small-scale

0.537

High

441010

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.518

High

441014

CXB2
Gap junction beta-2 protein

1

0

High-throughput

0.518

High

441034

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.518

High

135803

MA2B1
Lysosomal alpha-mannosidase

1

0

High-throughput

0.513

High

236871

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

High-throughput

0.513

High

313729

SVIL
Supervillin

1

0

High-throughput

0.513

High

397086

PAI1
Plasminogen activator inhibitor 1

1

0

High-throughput

0.513

High

413021

CHLE
Cholinesterase

1

0

High-throughput

0.513

High

433107

LAMB1
Laminin subunit beta-1

1

0

High-throughput

0.513

High

441015

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

High-throughput

0.513

High

441020

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

441022

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.513

High

441023

ARID2
AT-rich interactive domain-containing protein 2

1

0

High-throughput

0.513

High

441026

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

441027

RN133
E3 ubiquitin-protein ligase RNF133

1

0

High-throughput

0.513

High

441028

AP3S1
AP-3 complex subunit sigma-1

1

0

High-throughput

0.513

High

441039

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

0

High-throughput

0.513

High

441041

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.513

High

441043

EXO1
Exonuclease 1

1

0

High-throughput

0.513

High

441017

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.494

High

441006

ITAM
Integrin alpha-M

1

1

Small-scale

0.479

High

441009

ANXA7
Annexin A7

1

1

High-throughput

0.479

High

441012

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.458

High

441019

DIP2A
Disco-interacting protein 2 homolog A

1

0

Small-scale

0.458

High

72994

B4DT77
Annexin

1

1

High-throughput

0.445

High

441011

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.437

High

441025

CD177
CD177 antigen

1

0

Small-scale

0.426

High

108813

H0Y9L7
TATA-box binding protein associated factor 1

1

1

High-throughput

0.407

High

441016

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.282

High

441030

CANB2
Calcineurin subunit B type 2

1

0

High-throughput

0.282

High

68270

P20L1
PHD finger protein 20-like protein 1

1

0

High-throughput

0.279

Low

225120

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

0

High-throughput

0.279

Low

441021

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.279

Low

441024

TXD11
Thioredoxin domain-containing protein 11

1

0

High-throughput

0.279

Low

441029

PF21A
PHD finger protein 21A

1

0

High-throughput

0.279

Low

441031

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.279

Low

441032

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.279

Low

441033

BCAS3
BCAS3 microtubule associated cell migration factor

1

0

High-throughput

0.279

Low

441037

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

441040

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

441042

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.279

Low

441044

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.279

Low

441007

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.249

Low

441013

MZF1
Myeloid zinc finger 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024