HitPredict

Interactor 1: VA0D (P32366)
V-type proton ATPase subunit d (V-ATPase subunit d) (V-ATPase 39 kDa subunit) (V-ATPase subunit M39) (Vacuolar proton pump subunit d)
Gene: VMA6

Interactor 2: VPP2 (P37296)
V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)
Gene: STV1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 11592965, 30910982, 37968396, 28183979, 16429126
Identification Methods coimmunoprecipitation, affinity chromatography technology, biochemical, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~vATP-synt_AC39
Common GO terms GO:0000139 - Golgi membrane
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
and 5 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 345
Sc

1 890
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Mm
+ Hs
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024