Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: ARPC1 (P38328)
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARC40

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 10377407, 11805837, 11805826, 15485833, 16554755, 18467557, 18719252, 20071330, 37968396, 23583819, 12499356, 16429126, 18381280, 20207164
Identification Methods biochemical, coimmunoprecipitation, molecular sieving, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~WD40
Common GO terms GO:0005885 - Arp2/3 protein complex
GO:0015629 - actin cytoskeleton
GO:0030479 - actin cortical patch
GO:0034314 - Arp2/3 complex-mediated actin nucleation
GO:0045010 - actin nucleation
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 391
Sc

1 384
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024