Protein: EI2BG
Translation initiation factor eIF2B subunit gamma (GCD complex subunit GCD1) (Guanine nucleotide exchange factor subunit GCD1) (eIF2B GDP-GTP exchange factor subunit gamma)

Gene: EI2BG, GCD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P09032

Gene Ontology (top 5):
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
GO:0006446 - regulation of translational initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478403

EI2BB
Translation initiation factor eIF2B subunit beta

15

15

Small-scale

0.764

High

478402

EI2BE
Translation initiation factor eIF2B subunit epsilon

16

15

Small-scale

0.763

High

478386

EI2BD
Translation initiation factor eIF2B subunit delta

14

15

Small-scale

0.763

High

478388

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

11

1

Small-scale

0.758

High

478401

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

9

8

Small-scale

0.757

High

478387

EI2BA
Translation initiation factor eIF2B subunit alpha

10

15

Small-scale

0.757

High

478378

IF2B
Eukaryotic translation initiation factor 2 subunit beta

8

5

Small-scale

0.754

High

478377

EI2BG
Translation initiation factor eIF2B subunit gamma

2

15

Small-scale

0.601

High

478406

RSSA1
Small ribosomal subunit protein uS2A

2

3

Small-scale

0.595

High

439196

PDC1
Pyruvate decarboxylase isozyme 1

2

5

High-throughput

0.588

High

478391

RS2
Small ribosomal subunit protein uS5

2

2

Small-scale

0.584

High

478420

IST1
Vacuolar protein sorting-associated protein IST1

2

1

High-throughput

0.537

High

478412

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

2

1

Small-scale

0.521

High

478400

XPO1
Exportin-1

1

7

High-throughput

0.489

High

478411

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

5

High-throughput

0.489

High

149496

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

383426

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

409848

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

433354

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

434707

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

435678

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

436263

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.479

High

441615

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

478379

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

478380

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

478381

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

478382

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

478390

SIS1
Protein SIS1

1

7

High-throughput

0.479

High

478396

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

478407

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

478409

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

478413

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

478417

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

478418

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

478421

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

478423

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

478433

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

478410

ATR
Serine/threonine-protein kinase MEC1

1

3

High-throughput

0.470

High

478419

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

1

High-throughput

0.470

High

478405

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

478428

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

478389

KC11
Casein kinase I homolog 1

1

4

High-throughput

0.457

High

478424

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

1

High-throughput

0.457

High

478435

PKH2
Serine/threonine-protein kinase PKH2

1

2

High-throughput

0.457

High

394127

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

453358

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

478383

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

478384

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

478385

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

478392

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

478414

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

478404

TOR2
Serine/threonine-protein kinase TOR2

1

4

High-throughput

0.439

High

478415

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

High-throughput

0.439

High

478393

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

478394

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

478397

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

478398

BMH1
Protein BMH1

1

1

High-throughput

0.437

High

478422

H3
Histone H3

1

1

High-throughput

0.437

High

478425

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.437

High

478426

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.437

High

478427

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.437

High

478430

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.437

High

478431

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

478432

SGO1
Shugoshin

1

1

High-throughput

0.437

High

478434

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

450493

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

478395

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.426

High

478429

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.407

High

478399

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.269

Low

449266

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.265

Low

478436

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.261

Low

478408

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

478416

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025