HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S100Z (Q8WXG8)
Protein S100-Z (S100 calcium-binding protein Z)
Gene: S100Z

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 99
+	Hs
		685156 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AB_HUMAN (2-99): 8.78e-39: 126: 31.63
+	Hs
		615205 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A1_HUMAN (1-94): 6.61e-38: 124: 57.45
+	Hs
		689702 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AA_HUMAN (1-99): 2.16e-36: 120: 44.44
+	Hs
		638928 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100P_HUMAN (3-93): 1.58e-34: 115: 51.65
+	Hs
		642918 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A4_HUMAN (1-90): 7.21e-33: 111: 46.67
+	Hs
		661206 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A2_HUMAN (1-92): 2.41e-32: 109: 42.39
+	Hs
		416365 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A9_HUMAN (3-98): 1.33e-31: 108: 35.05
+	Hs
		689700 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A3_HUMAN (1-90): 6.14e-31: 106: 37.78
+	Hs
		380746 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100B_HUMAN (3-93): 1.16e-30: 105: 45.06
+	Hs
		689703 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AC_HUMAN (3-93): 6.02e-30: 103: 39.56
+	Hs
		396691 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A8_HUMAN (1-97): 3.9e-29: 101: 28.87
+	Hs
		416580 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A6_HUMAN (1-90): 1.58e-27: 97.6: 38.89
+	Hs
		689699 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A5_HUMAN (1-95): 9.37e-26: 93.4: 43.16
+	Hs
		689706 NAC1_HUMAN (1-973): 0: 1131: 100.00		S1A7A_HUMAN (3-98): 9.4e-25: 91.1: 24.49
+	Hs
		678415 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A7_HUMAN (3-98): 1.2e-23: 88: 24.49
+	Hs
		689708 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AD_HUMAN (3-84): 9.92e-23: 85.7: 29.27
+	Hs
		689709 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AE_HUMAN (3-84): 8.69e-21: 81.1: 21.95
+	Hs
		666669 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100G_HUMAN (5-84): 1.62e-19: 76.8: 38.75