HitPredict

Interactor 1: ASF1 (P32447)
Histone chaperone ASF1 (Anti-silencing function protein 1) (yASF1)
Gene: ASF1

Interactor 2: HIR2 (P32480)
Protein HIR2 (Histone transcription regulator 2)
Gene: HIR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.743

Property	Details
Experiments	11412995, 16554755, 16303565, 24824343, 37968396, 20048053, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 279 Sc			1 875
+	Dm
		184546 ASF1_DROME (1-182): 4.94e-96: 283: 49.74		HIRA_DROME (1-871): 2.16e-128: 413: 14.01
+	Sc
		689846 ASF1_YEAST (1-279): 1.29e-110: 322: 100.00		HIR1_YEAST (1-542): 6.88e-84: 288: 17.77
+	Xl
		993165 AS1AA_XENLA (1-175): 4.88e-101: 295: 53.67		Q07CZ6_XENLA (23-529): 5.02e-80: 271: 14.83
+	Dm
		53064 ASF1_DROME (1-182): 4.94e-96: 283: 49.74		A1Z898_DROME (7-513): 3.11e-72: 254: 14.21
+	Sc
		689955 ASF1_YEAST (1-279): 1.29e-110: 322: 100.00		CAC2_YEAST (63-409): 1.11e-58: 209: 18.80
+	Sp
		144001 ASF1_SCHPO (1-169): 1.68e-88: 265: 62.29		YEG3_SCHPO (8-411): 3.63e-50: 187: 15.35
+	Hs
		867897 ASF1B_HUMAN (1-167): 4.44e-107: 310: 55.36		HIRA_HUMAN (202-540): 5.57e-28: 123: 10.24
+	Hs
		867906 ASF1A_HUMAN (1-158): 3.13e-99: 290: 57.60		HIRA_HUMAN (202-540): 5.57e-28: 123: 10.24
+	Sp
		251629 ASF1_SCHPO (1-169): 1.68e-88: 265: 62.29		HIR1_SCHPO (201-546): 2.11e-34: 144: 9.89
+	Xl
		1148535 AS1AA_XENLA (1-175): 4.88e-101: 295: 53.67		HIRA_XENLA (273-649): 1.77e-24: 112: 10.63
+	Gg
		945614 ASF1_CHICK (1-158): 3.13e-99: 290: 57.60		HIRA_CHICK (275-644): 3.57e-24: 111: 10.57
+	Hs
		1024600 ASF1B_HUMAN (1-167): 4.44e-107: 310: 55.36		CAF1B_HUMAN (267-425): 9.95e-11: 67.3: 8.56
+	At
		1321245 ASF1A_ARATH (1-195): 1.5e-103: 301: 48.72		HIRA_ARATH (8-188): 2.99e-12: 72.9: 9.43
+	Hs
		1024612 ASF1A_HUMAN (1-158): 3.13e-99: 290: 57.60		CAF1B_HUMAN (267-425): 9.95e-11: 67.3: 8.56
+	Gg
		1107997 ASF1_CHICK (1-158): 3.13e-99: 290: 57.60		CAF1B_CHICK (267-440): 1.21e-10: 66.9: 8.96
+	Sp
		251229 ASF1_SCHPO (1-169): 1.68e-88: 265: 62.29		SLM9_SCHPO (4-190): 3.68e-14: 78.7: 6.67