Interactor 1: DPH2 (P32461)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)
Gene: DPH2
Interactor 2: DPH1 (P40487)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Gene: DPH1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11283351, 23645155, 18719252, 24422557, 16554755, 16429126, 37968396, 38672486 |
| Identification Methods | two hybrid pooling approach, affinity chromatography technology, two hybrid, pull down, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Diphthamide_syn~Diphthamide_syn |
| Common GO terms | GO:0005737 - cytoplasm GO:0017183 - protein histidyl modification to diphthamide GO:0032991 - protein-containing complex GO:0046872 - metal ion binding GO:0051539 - 4 iron, 4 sulfur cluster binding and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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| + | Hs | |
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| + | Ph | |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
