Protein: ISL2
Insulin gene enhancer protein ISL-2 (Islet-2)

Gene: ISL2
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q96A47

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1281161

LHX4
LIM/homeobox protein Lhx4

6

18

Small-scale

0.947

High

1199129

LDB1
LIM domain-binding protein 1

4

20

High-throughput

0.894

High

1283500

LHX3
LIM/homeobox protein Lhx3

3

19

Small-scale

0.866

High

638365

RBTN2
Rhombotin-2

2

19

High-throughput

0.811

High

903764

LMO4
LIM domain transcription factor LMO4

2

19

High-throughput

0.789

High

1283496

SSBP3
Single-stranded DNA-binding protein 3

5

20

High-throughput

0.718

High

946656

SSBP2
Single-stranded DNA-binding protein 2

4

20

High-throughput

0.694

High

238115

LMX1B
LIM homeobox transcription factor 1-beta

1

19

High-throughput

0.691

High

638556

RBTN1
Rhombotin-1

1

18

High-throughput

0.691

High

822660

LHX1
LIM/homeobox protein Lhx1

1

17

High-throughput

0.691

High

1251421

LMO3
LIM domain only protein 3

1

19

High-throughput

0.691

High

1283495

SSBP4
Single-stranded DNA-binding protein 4

3

20

High-throughput

0.667

High

899930

ISL1
Insulin gene enhancer protein ISL-1

1

20

Small-scale

0.647

High

1283503

ARI1
E3 ubiquitin-protein ligase ARIH1

2

3

High-throughput

0.628

High

197794

CRX
Cone-rod homeobox protein

1

18

High-throughput

0.618

High

839800

LHX2
LIM/homeobox protein Lhx2

1

18

High-throughput

0.618

High

1148484

LHX8
LIM/homeobox protein Lhx8

1

18

High-throughput

0.618

High

131737

BCL9
B-cell CLL/lymphoma 9 protein

2

20

High-throughput

0.611

High

1283497

IDI2
Isopentenyl-diphosphate delta-isomerase 2

2

2

High-throughput

0.611

High

1283494

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

5

High-throughput

0.552

High

974124

DYST
Dystonin

1

1

High-throughput

0.536

High

1135494

RN187
E3 ubiquitin-protein ligase RNF187

1

3

High-throughput

0.536

High

1272517

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

1283498

PICK1
PRKCA-binding protein

1

2

High-throughput

0.536

High

1283502

PYGO1
Pygopus homolog 1

1

20

High-throughput

0.536

High

1061390

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.513

High

1238572

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

1283499

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.513

High

1283501

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.513

High

875883

MFAP4
Microfibril-associated glycoprotein 4

1

1

High-throughput

0.489

High

1236215

CA052
UPF0690 protein C1orf52

1

2

High-throughput

0.489

High

505273

EGR2
E3 SUMO-protein ligase EGR2

1

10

High-throughput

0.479

High

507485

ERG
Transcriptional regulator ERG

1

6

High-throughput

0.479

High

575532

EGR1
Early growth response protein 1

1

9

High-throughput

0.479

High

818332

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

831556

CEBPA
CCAAT/enhancer-binding protein alpha

1

10

High-throughput

0.479

High

1200126

BCL9L
B-cell CLL/lymphoma 9-like protein

1

20

High-throughput

0.479

High

1254878

SP7
Transcription factor Sp7

1

11

High-throughput

0.479

High

1283504

ORC6
Origin recognition complex subunit 6

1

2

High-throughput

0.479

High

1044023

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.445

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024