HitPredict

Interactor 1: EMRA (P27303)
Multidrug export protein EmrA
Gene: EMRA

Interactor 2: EMRA (P27303)
Multidrug export protein EmrA
Gene: EMRA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 24561554, 19805313
Identification Methods two hybrid, surface plasmon resonance, cross-linking study, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CusB_dom_1~CusB_dom_1, CusB_dom_1~HlyD_D23, HlyD_D23~HlyD_D23
Common GO terms GO:0005886 - plasma membrane
GO:0009636 - response to toxic substance
GO:0015125 - bile acid transmembrane transporter activity
GO:0015721 - bile acid and bile salt transport
GO:0030288 - outer membrane-bounded periplasmic space
and 7 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 390
Ec

1 390
+ Ec
+ Ec
+ Ns
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025